PKBDO8101SVXI
{
"@context": "/terms/",
"@id": "/human-donors/PKBDO8101SVXI/",
"@type": [
"HumanDonor",
"Donor",
"Item"
],
"aab_gada": false,
"aab_gada_value": 0,
"aab_ia2": false,
"aab_ia2_value": 0,
"aab_iaa": false,
"aab_iaa_value": -0.002,
"aab_znt8": false,
"aab_znt8_value": -0.005,
"accession": "PKBDO8101SVXI",
"age": 38,
"aliases": [
"klaus-kaestner:HPAP-094"
],
"audit": {
"WARNING": [
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 2 field `glucose_loweing_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier2_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `biological_sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `aab_gada_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `aab_ia2_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `aab_iaa_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `aab_znt8_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `other_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO8101SVXI](/human-donors/PKBDO8101SVXI/) is missing tier 3 field `related_donors`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO8101SVXI/"
}
]
},
"award": {
"@id": "/awards/UC4DK112217/"
},
"bmi": 37.84,
"c_peptide": 9.43,
"cause_of_death": "Cerebrovascular/Stroke",
"center_donor_id": "SAMN22562805",
"collections": [
"HPAP"
],
"creation_timestamp": "2024-12-03T20:16:11.303977+00:00",
"data_available": [
{
"dataset": "Genotyping",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "HLA_typing",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "CODEX",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "TCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "BCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Peripheral_blood"
}
],
"dbxrefs": [
"PANC-DB:HPAP-094"
],
"derived_diabetes_status": "Normal",
"description": "Human donor SAMN22562805 in the HPAP database",
"diabetes_duration": "20",
"diabetes_status": [
"/phenotype-terms/MONDO_0005147/"
],
"diabetes_status_description": "type 1 diabetes",
"donation_type": "Donation after Brain Death",
"ethnicities": [
"White"
],
"family_history_of_diabetes": "true",
"family_history_of_diabetes_relationship": [
"Father",
"grandfather"
],
"genetic_ethnicities": [
{
"ethnicity": "European",
"percentage": 100
}
],
"hba1c": 5,
"hla_typing": [
"A,02:01-23:01,NGS",
"B,15:01-44:02,NGS",
"C,03:03-05:01,NGS",
"DPA1,01:03-.,NGS",
"DPB1,03:01-04:01,NGS",
"DQA1,03:03-05:05,NGS",
"DQB1,03:01-.,NGS",
"DRB1,04:01-11:01,NGS",
"DRB3,02:02-.,NGS",
"DRB4,.-01:03,NGS",
"DRB5,.-.,NGS",
"A,02-23,RT-PCR",
"B,15(62)-44,RT-PCR",
"Bw4,1-1,RT-PCR",
"Bw6,1-1,RT-PCR",
"C,03(9)-05,RT-PCR",
"DPB1,03:01-04:01,RT-PCR",
"DQA1,03-05,RT-PCR",
"DQB1,7-7,RT-PCR",
"DR,4-11,RT-PCR",
"DR51,0-0,RT-PCR",
"DR52,52-0,RT-PCR",
"DR53,53-0,RT-PCR"
],
"hospital_stay": 57,
"human_donor_identifiers": [
"PANC-DB:HPAP-094"
],
"lab": {
"@id": "/labs/klaus-kaestner/",
"title": "Klaus Kaestner, UPenn"
},
"living_donor": false,
"notes": "Cohort_ID:HPAP-094;skin cancer, deep vein thrombosis, transient ischemic attack, asthma, obesity, hypothyroidism, migraines, orthostatic hypotension, depression, anxiety",
"other_tissues_available": [
"/sample-terms/UBERON_0002113/",
"/sample-terms/UBERON_0002107/",
"/sample-terms/UBERON_0001264/"
],
"pancreas_tissue_available": true,
"publication_identifiers": [
"PMID:31127054",
"PMID:36206763"
],
"release_timestamp": "2025-01-10T01:41:15.052557+00:00",
"rrid": "RRID:SAMN22562805",
"schema_version": "18",
"sex": "female",
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitter_comment": "Meta-data was obtained directly from PANC-DB",
"summary": "White female /phenotype-terms/MONDO_0005147/",
"t1d_stage": "Stage 3: One or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis",
"taxa": "Homo sapiens",
"url": "https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-094",
"uuid": "e1c798e5-0b0a-46d7-8586-a47f8c217307",
"virtual": false
}
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
