PKBDO5476TMJJ
{
"@context": "/terms/",
"@id": "/human-donors/PKBDO5476TMJJ/",
"@type": [
"HumanDonor",
"Donor",
"Item"
],
"aab_count": 0,
"aab_gada": false,
"aab_gada_assay": [],
"aab_gada_value": 13,
"aab_ia2": false,
"aab_ia2_assay": [],
"aab_ia2_value": 0,
"aab_iaa": false,
"aab_iaa_assay": [],
"aab_iaa_value": -0.001,
"aab_positive": false,
"aab_summary": "none positive",
"aab_tested": true,
"aab_znt8": false,
"aab_znt8_assay": [],
"aab_znt8_value": -0.003,
"accession": "PKBDO5476TMJJ",
"age": 56,
"age_group": "40-64",
"aliases": [
"klaus-kaestner:HPAP-096"
],
"audit": {
"WARNING": [
{
"category": "missing tier 1 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 1 field `sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier1_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 2 field `glucose_loweing_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier2_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `related_donors`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
}
]
},
"award": {
"@id": "/awards/U01DK123594/",
"name": "U01DK123594",
"title": "THE HUMAN PANCREAS ANALYSIS PROGRAM FOR TYPE 2 DIABETES"
},
"biosamples": [
"/primary-islet/PKBSM2200JUWJ/",
"/primary-cells/PKBSM2974ZKOX/",
"/primary-cells/PKBSM6109AYRB/",
"/primary-islet/PKBSM7146TCHE/"
],
"bmi": 38.7,
"c_peptide": 1.78,
"cause_of_death": "Cerebrovascular/Stroke",
"center_donor_id": "SAMN22562807",
"collections": [
"HPAP"
],
"creation_timestamp": "2024-10-14T22:34:53.730187+00:00",
"data_available": [
{
"dataset": "Genotyping",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "HLA_typing",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "RNAseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "scRNAseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Function",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Imaging",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "CyTof",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "CODEX",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "imaging_mass_spec",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
}
],
"data_available_datasets": [
"Genotyping",
"HLA_typing",
"RNAseq",
"scRNAseq",
"Function",
"Imaging",
"CyTof",
"Histology",
"CODEX",
"imaging_mass_spec"
],
"data_available_keys": [
"Genotyping|unspecified",
"HLA_typing|unspecified",
"RNAseq|Islet",
"scRNAseq|Islet",
"Function|Islet",
"Imaging|Islet",
"CyTof|Islet",
"Histology|Pancreas",
"CODEX|Pancreas",
"imaging_mass_spec|Pancreas",
"Histology|Spleen",
"Histology|Lymph"
],
"data_available_tissues": [
"unspecified",
"Islet",
"Pancreas",
"Spleen",
"Lymph"
],
"dbxrefs": [
"PANC-DB:HPAP-096"
],
"derived_diabetes_status": "Diabetes",
"description": "Human pancreas donor SAMN22562807 in the HPAP database",
"diabetes_duration": "1",
"diabetes_status": [
"/phenotype-terms/MONDO_0005148/"
],
"diabetes_status_description": "Type 2 Diabetes",
"dominant_genetic_ancestry": "Admixed-American",
"donation_type": "Donation after brain death",
"ethnicities": [
"Hispanic"
],
"family_history_of_diabetes": "-",
"gender": "Female",
"genetic_ethnicities": [
{
"ethnicity": "Admixed-American",
"percentage": 100
}
],
"genetic_sex": "Female",
"hba1c": 7.7,
"hla_status": "X/X",
"hla_typing": [
"A,24-24,RT-PCR",
"B,62-65,RT-PCR",
"Bw4,0-0,RT-PCR",
"Bw6,1-1,RT-PCR",
"C,08-09,RT-PCR",
"DPB1,04:01-04:01,RT-PCR",
"DQA1,04-05,RT-PCR",
"DQB1,4-7,RT-PCR",
"DR,8-11,RT-PCR",
"DR51,0-0,RT-PCR",
"DR52,52-.,RT-PCR",
"DR53,0-0,RT-PCR"
],
"hospital_stay": 136,
"human_donor_identifiers": [
"PANC-DB:HPAP-096"
],
"lab": {
"@id": "/labs/klaus-kaestner/"
},
"label_hba1c_discordant": false,
"living_donor": false,
"notes": "other disease states: Hyperlipidemia, Hypertension",
"other_therapy": [
"Unknown medication"
],
"other_tissues_available": [
"/sample-terms/UBERON_0002113/",
"/sample-terms/UBERON_0001264/",
"/sample-terms/UBERON_0000948/"
],
"pancreas_tissue_available": true,
"pediatric": false,
"publication_identifiers": [
"PMID:31127054",
"PMID:36206763"
],
"release_timestamp": "2025-01-10T01:41:14.137268+00:00",
"rrid": "RRID:SAMN22562807",
"schema_version": "23",
"sex_discordant": false,
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitter_comment": "Meta-data was obtained directly from PANC-DB",
"summary": "PKBDO5476TMJJ",
"t1d_stage": "No sufficient information to derive",
"taxa": "Homo sapiens",
"tier1_complete": true,
"url": "https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-096",
"uuid": "d9a62854-bb47-42b1-ac11-44f28065caba",
"virtual": false
}
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
