{
"@context": "/terms/",
"@id": "/human-donors/PKBDO4259MLYO/",
"@type": [
"HumanDonor",
"Donor",
"Item"
],
"aab_gada": true,
"aab_gada_value": 567,
"aab_ia2": false,
"aab_ia2_value": 0,
"aab_iaa": false,
"aab_iaa_value": -0.006,
"aab_znt8": false,
"aab_znt8_value": -0.004,
"accession": "PKBDO4259MLYO",
"age": 42,
"aliases": [
"klaus-kaestner:HPAP-010"
],
"audit": {
"WARNING": [
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO4259MLYO](/human-donors/PKBDO4259MLYO/) is missing tier 2 field `diabetes_status_hba1c`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/human-donors/PKBDO4259MLYO/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO4259MLYO](/human-donors/PKBDO4259MLYO/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO4259MLYO/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO4259MLYO](/human-donors/PKBDO4259MLYO/) is missing tier 3 field `biological_sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO4259MLYO/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO4259MLYO](/human-donors/PKBDO4259MLYO/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO4259MLYO/"
}
]
},
"award": {
"@id": "/awards/UC4DK112217/"
},
"bmi": 36.8,
"c_peptide": 5.27,
"cause_of_death": "Head Trauma",
"center_donor_id": "SAMN19776442",
"collections": [
"HPAP"
],
"creation_timestamp": "2024-10-14T22:30:04.008672+00:00",
"data_available": [
{
"dataset": "Genotyping",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "HLA_typing",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "RNAseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "ATAC-seq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Function",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Morphology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "CyTof",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "imaging_mass_spec",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "TCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "BCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Peripheral_blood"
}
],
"dbxrefs": [
"PANC-DB:HPAP-010"
],
"description": "Human pancreas donor SAMN19776442 in the HPAP database",
"diabetes_duration": "2",
"diabetes_status": [
"/phenotype-terms/MONDO_0005148/"
],
"diabetes_status_description": "type 2 diabetes",
"donation_type": "DBD",
"ethnicities": [
"Caucasian"
],
"family_history_of_diabetes": "true",
"family_history_of_diabetes_relationship": [
"Father",
"Sister"
],
"genetic_ethnicities": [
{
"ethnicity": "European",
"percentage": 97
},
{
"ethnicity": "African",
"percentage": 2
},
{
"ethnicity": "Admixed-American",
"percentage": 1
}
],
"glucose_loweing_theraphy": [
"Glipizide"
],
"hba1c": 6,
"hla_typing": [
"A,02-32,RT-PCR",
"A,02:01-32:01,NGS",
"B,15:01-44:02,NGS",
"B,44-62,RT-PCR",
"Bw4,ND-ND,RT-PCR",
"Bw6,ND-ND,RT-PCR",
"C,03:03-05:01,NGS",
"C,ND-ND,RT-PCR",
"DPA1,01:03-02:07,NGS",
"DPB1,03:01-19:01,NGS",
"DPB1,ND-ND,RT-PCR",
"DQA1,01:02-05:01,NGS",
"DQA1,ND-ND,RT-PCR",
"DQB1,02:01-06:02,NGS",
"DQB1,ND-ND,RT-PCR",
"DR,15-17,RT-PCR",
"DRB1,15:01-03:01,NGS",
"DRB3,.-01:01,NGS",
"DRB4,.-.,NGS",
"DRB5,01:01-.,NGS"
],
"hospital_stay": 62,
"human_donor_identifiers": [
"PANC-DB:HPAP-010"
],
"lab": {
"@id": "/labs/klaus-kaestner/",
"title": "Klaus Kaestner, UPenn"
},
"living_donor": false,
"notes": "other disease states: Hyperlipidemia, Hypertension",
"other_tissues_available": [
"/sample-terms/UBERON_0002113/",
"/sample-terms/UBERON_0002107/"
],
"pancreas_tissue_available": true,
"publication_identifiers": [
"PMID:31127054",
"PMID:36206763"
],
"release_timestamp": "2025-01-10T01:41:04.266954+00:00",
"rrid": "RRID:SAMN19776442",
"schema_version": "16",
"sex": "female",
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitter_comment": "Meta-data was obtained directly from PANC-DB",
"summary": "Caucasian female /phenotype-terms/MONDO_0005148/",
"taxa": "Homo sapiens",
"url": "https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-010",
"uuid": "1737784d-786b-4c04-8f19-d6844cc7c4d9",
"virtual": false
}