released

PKBDO4259MLYO

released

RRID RRID:SAMN19776442Program Donor ID SAMN19776442

Clinical summary

Diabetes status

Type 1 Diabetes

Age (y)

Age group

40-64

BMI

36.8

Height (cm)

—

Weight (kg)

—

HbA1c %

C-Peptide (ng/ml)

5.27

Diabetes duration

AAB summary

GADA+

AAB count

Age (y): 42
Age group: 40-64
Pediatric: No
Gender: Female
Genetic Sex: Female
Sex discordant: No
Ethnicity: White
Predicted genetic ancestry: European (97%), African (2%), Admixed-American (1%)
Dominant genetic ancestry: European

Diabetes (ontology): MONDO:0005147
T1D stage: Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
Tier 1 complete: Yes
Family history of diabetes: TRUE
Family history relationship: Father, Sister
Living donor: No
Cause of death: Head Trauma
Donation type: Donation after brain death
Hospital stay (h): 62
Medication: Glipizide

GADAPositive

567 unit/ml

IAANegative

-0.006 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

-0.004 unit/ml

Locus	Allele 1	Allele 2	Method
A	02	32	RT-PCR
A	02:01	32:01	NGS
B	15:01	44:02	NGS
B	44	62	RT-PCR
Bw4	ND	ND	RT-PCR
Bw6	ND	ND	RT-PCR
C	03:03	05:01	NGS
C	ND	ND	RT-PCR
DPA1	01:03	02:07	NGS
DPB1	03:01	19:01	NGS
DPB1	ND	ND	RT-PCR
DQA1	01:02	05:01	NGS
DQA1	ND	ND	RT-PCR
DQB1	02:01	06:02	NGS
DQB1	ND	ND	RT-PCR
DR	15	17	RT-PCR
DRB1	15:01	03:01	NGS
DRB3	—	01:01	NGS
DRB4	—	—	NGS
DRB5	01:01	—	NGS

Datasets: Genotyping, HLA_typing, RNAseq, ATAC-seq, Function, Morphology, CyTof, Histology, imaging_mass_spec, TCRseq, BCRseq, Flow_cytometry
Tissues: unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood