PKBDO4145OHBN

{
    "@context": "/terms/",
    "@id": "/human-donors/PKBDO4145OHBN/",
    "@type": [
        "HumanDonor",
        "Donor",
        "Item"
    ],
    "aab_gada": false,
    "aab_gada_value": 0,
    "aab_ia2": false,
    "aab_ia2_value": 0,
    "aab_iaa": false,
    "aab_iaa_value": 0,
    "aab_znt8": false,
    "aab_znt8_value": 0.001,
    "accession": "PKBDO4145OHBN",
    "age": 59,
    "aliases": [
        "klaus-kaestner:HPAP-109"
    ],
    "audit": {
        "WARNING": [
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO4145OHBN](/human-donors/PKBDO4145OHBN/) is missing tier 2 field `diabetes_status_hba1c`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/human-donors/PKBDO4145OHBN/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO4145OHBN](/human-donors/PKBDO4145OHBN/) is missing tier 3 field `phenotypic_features`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO4145OHBN/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO4145OHBN](/human-donors/PKBDO4145OHBN/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO4145OHBN/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO4145OHBN](/human-donors/PKBDO4145OHBN/) is missing tier 3 field `biological_sex`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO4145OHBN/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO4145OHBN](/human-donors/PKBDO4145OHBN/) is missing tier 3 field `documents`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO4145OHBN/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U01DK123594/"
    },
    "bmi": 29.49,
    "c_peptide": 1.44,
    "cause_of_death": "Cerebrovascular/Stroke",
    "center_donor_id": "SAMN25600005",
    "collections": [
        "HPAP"
    ],
    "creation_timestamp": "2024-10-14T22:35:10.145185+00:00",
    "data_available": [
        {
            "dataset": "Genotyping",
            "dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
            "dataset_tissue": "-"
        },
        {
            "dataset": "HLA_typing",
            "dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
            "dataset_tissue": "-"
        },
        {
            "dataset": "scRNAseq",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "snATACseq",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "Function",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "Imaging",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "CyTof",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "histology",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Pancreas"
        },
        {
            "dataset": "histology",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Spleen"
        },
        {
            "dataset": "histology",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Lymph"
        }
    ],
    "dbxrefs": [
        "PANC-DB:HPAP-109"
    ],
    "description": "Human pancreas donor SAMN25600005 in the HPAP database",
    "diabetes_duration": "5",
    "diabetes_status": [
        "/phenotype-terms/MONDO_0005148/"
    ],
    "diabetes_status_description": "type 2 diabetes",
    "donation_type": "DCD",
    "ethnicities": [
        "Hispanic"
    ],
    "family_history_of_diabetes": "false",
    "genetic_ethnicities": [
        {
            "ethnicity": "East-Asian",
            "percentage": 88
        },
        {
            "ethnicity": "European",
            "percentage": 7
        },
        {
            "ethnicity": "Admixed-American",
            "percentage": 4
        },
        {
            "ethnicity": "African",
            "percentage": 1
        }
    ],
    "glucose_loweing_theraphy": [
        "Metformin"
    ],
    "hba1c": 7.5,
    "hla_typing": [
        "A,11-34,RT-PCR",
        "B,13-61,RT-PCR",
        "Bw4,1-1,RT-PCR",
        "Bw6,1-1,RT-PCR",
        "C,10-15,RT-PCR",
        "DPB1,01:01-05:01,RT-PCR",
        "DQA1,01-01,RT-PCR",
        "DQB1,5-6,RT-PCR",
        "DR,15-15,RT-PCR",
        "DR51,5:01-.,RT-PCR",
        "DR52,0-0,RT-PCR",
        "DR53,0-.,RT-PCR"
    ],
    "hospital_stay": 70,
    "human_donor_identifiers": [
        "PANC-DB:HPAP-109"
    ],
    "lab": {
        "@id": "/labs/klaus-kaestner/",
        "title": "Klaus Kaestner, UPenn"
    },
    "living_donor": false,
    "notes": "other disease states: Autoimmune disease, Hyperlipidemia, Hypertension",
    "other_tissues_available": [
        "/sample-terms/UBERON_0001264/"
    ],
    "pancreas_tissue_available": true,
    "publication_identifiers": [
        "PMID:31127054",
        "PMID:36206763"
    ],
    "release_timestamp": "2025-01-10T01:41:39.640022+00:00",
    "rrid": "RRID:SAMN25600005",
    "schema_version": "16",
    "sex": "female",
    "status": "released",
    "submitted_by": {
        "@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
        "title": "Ying Sun"
    },
    "submitter_comment": "Meta-data was obtained directly from PANC-DB",
    "summary": "Hispanic female /phenotype-terms/MONDO_0005148/",
    "taxa": "Homo sapiens",
    "url": "https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-109",
    "uuid": "b57260c6-a1e8-4be7-8ab2-63b45eaac226",
    "virtual": false
}