PKBDO2126ZQOL
{
"@context": "/terms/",
"@id": "/human-donors/PKBDO2126ZQOL/",
"@type": [
"HumanDonor",
"Donor",
"Item"
],
"aab_count": 1,
"aab_gada": true,
"aab_gada_assay": [
"1"
],
"aab_gada_value": 95,
"aab_ia2": false,
"aab_ia2_assay": [],
"aab_ia2_value": 0,
"aab_iaa": false,
"aab_iaa_assay": [],
"aab_iaa_value": 0.006,
"aab_positive": true,
"aab_summary": "GADA+",
"aab_tested": true,
"aab_znt8": false,
"aab_znt8_assay": [],
"aab_znt8_value": -0.005,
"accession": "PKBDO2126ZQOL",
"age": 3,
"age_group": "0-12",
"aliases": [
"klaus-kaestner:HPAP-009"
],
"audit": {
"WARNING": [
{
"category": "missing tier 1 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 1 field `sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier1_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 2 field `hba1c`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier2_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 2 field `glucose_loweing_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier2_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 3 field `diabetes_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 3 field `other_therapy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 3 field `derived_diabetes_status`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2126ZQOL](/human-donors/PKBDO2126ZQOL/) is missing tier 3 field `related_donors`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO2126ZQOL/"
}
]
},
"award": {
"@id": "/awards/UC4DK112217/",
"name": "UC4DK112217",
"title": "PENN INTEGRATED HUMAN PANCREAS PROCUREMENT AND ANALYSIS PROGRAM"
},
"biosamples": [
"/primary-islet/PKBSM5748NUYT/",
"/primary-cells/PKBSM0316FYVW/",
"/primary-cells/PKBSM8942UJMA/",
"/primary-cells/PKBSM4414HLFA/",
"/primary-islet/PKBSM0941ZGAK/"
],
"bmi": 14.9,
"c_peptide": 0.69,
"cause_of_death": "Head Trauma",
"center_donor_id": "SAMN19776441",
"collections": [
"HPAP"
],
"creation_timestamp": "2024-10-14T22:30:01.912791+00:00",
"data_available": [
{
"dataset": "Genotyping",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "HLA_typing",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "RNAseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "ATAC-seq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Function",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Morphology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "CyTof",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "WGBS",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "CODEX",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "imaging_mass_spec",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "TCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "BCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
}
],
"data_available_datasets": [
"Genotyping",
"HLA_typing",
"RNAseq",
"ATAC-seq",
"Function",
"Morphology",
"CyTof",
"WGBS",
"Histology",
"CODEX",
"imaging_mass_spec",
"TCRseq",
"BCRseq",
"Flow_cytometry"
],
"data_available_keys": [
"Genotyping|unspecified",
"HLA_typing|unspecified",
"RNAseq|Islet",
"ATAC-seq|Islet",
"Function|Islet",
"Morphology|Islet",
"CyTof|Islet",
"WGBS|Islet",
"Histology|Pancreas",
"CODEX|Pancreas",
"imaging_mass_spec|Pancreas",
"TCRseq|Spleen",
"BCRseq|Spleen",
"Flow_cytometry|Spleen",
"Histology|Spleen",
"Histology|Lymph"
],
"data_available_tissues": [
"unspecified",
"Islet",
"Pancreas",
"Spleen",
"Lymph"
],
"dbxrefs": [
"PANC-DB:HPAP-009"
],
"description": "Human pancreas donor SAMN19776441 in the HPAP database",
"diabetes_status": [],
"diabetes_status_description": "Control Without Diabetes",
"dominant_genetic_ancestry": "African",
"donation_type": "Donation after brain death",
"ethnicities": [
"African American"
],
"family_history_of_diabetes": "FALSE",
"gender": "Male",
"genetic_ethnicities": [
{
"ethnicity": "African",
"percentage": 44
},
{
"ethnicity": "Admixed-American",
"percentage": 26
},
{
"ethnicity": "European",
"percentage": 14
},
{
"ethnicity": "South-Asian",
"percentage": 11
},
{
"ethnicity": "East-Asian",
"percentage": 5
}
],
"genetic_sex": "Male",
"hla_typing": [
"A,01:01-24:03,NGS",
"A,1-24,RT-PCR",
"B,08:01-51:01,NGS",
"B,8-51,RT-PCR",
"C,07:01-15:02,NGS",
"C,7-15,RT-PCR",
"DPA1,01-02,RT-PCR",
"DPA1,01:03-02:01,NGS",
"DPB1,04:01-13:01G,NGS",
"DQA1,01-01,RT-PCR",
"DQA1,01:01-01:02,NGS",
"DQB1,05-05,RT-PCR",
"DQB1,05:01-05:02,NGS",
"DRB1,01-16,RT-PCR",
"DRB1,01:01-16:02,NGS",
"DRB5,.-02:02,NGS"
],
"hospital_stay": 118,
"human_donor_identifiers": [
"PANC-DB:HPAP-009"
],
"lab": {
"@id": "/labs/klaus-kaestner/"
},
"living_donor": false,
"other_tissues_available": [
"/sample-terms/UBERON_0001264/"
],
"pancreas_tissue_available": true,
"pediatric": true,
"publication_identifiers": [
"PMID:31127054",
"PMID:36206763"
],
"release_timestamp": "2025-01-10T01:41:04.048758+00:00",
"rrid": "RRID:SAMN19776441",
"schema_version": "23",
"sex_discordant": false,
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitter_comment": "Meta-data was obtained directly from PANC-DB",
"summary": "PKBDO2126ZQOL",
"t1d_stage": "No sufficient information to derive",
"taxa": "Homo sapiens",
"tier1_complete": false,
"url": "https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-009",
"uuid": "b5370313-cccb-4b16-881c-7c020bd59fa4",
"virtual": false
}
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
