PKBDO1723DEAS

{
    "@context": "/terms/",
    "@id": "/human-donors/PKBDO1723DEAS/",
    "@type": [
        "HumanDonor",
        "Donor",
        "Item"
    ],
    "aab_gada": false,
    "aab_gada_value": 0,
    "aab_ia2": false,
    "aab_ia2_value": 0,
    "aab_iaa": false,
    "aab_iaa_value": 0,
    "aab_znt8": false,
    "aab_znt8_value": 0.002,
    "accession": "PKBDO1723DEAS",
    "age": 45,
    "aliases": [
        "klaus-kaestner:HPAP-083"
    ],
    "audit": {
        "WARNING": [
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 2 field `diabetes_status_hba1c`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/human-donors/PKBDO1723DEAS/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `phenotypic_features`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO1723DEAS/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO1723DEAS/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `biological_sex`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO1723DEAS/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `documents`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_optional_fields",
                "path": "/human-donors/PKBDO1723DEAS/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U01DK123594/"
    },
    "bmi": 35.62,
    "c_peptide": 4.35,
    "cause_of_death": "Anoxia",
    "center_donor_id": "SAMN19842612",
    "collections": [
        "HPAP"
    ],
    "creation_timestamp": "2024-10-14T22:34:38.532558+00:00",
    "data_available": [
        {
            "dataset": "Genotyping",
            "dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
            "dataset_tissue": "-"
        },
        {
            "dataset": "HLA_typing",
            "dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
            "dataset_tissue": "-"
        },
        {
            "dataset": "RNAseq",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "scRNAseq",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "snATACseq",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "Function",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "Imaging",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "Morphology",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "CyTof",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Islet"
        },
        {
            "dataset": "histology",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Pancreas"
        },
        {
            "dataset": "CODEX",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Pancreas"
        },
        {
            "dataset": "imaging_mass_spec",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Pancreas"
        },
        {
            "dataset": "histology",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Spleen"
        },
        {
            "dataset": "histology",
            "dataset_link": "https://hpap.pmacs.upenn.edu",
            "dataset_tissue": "Lymph"
        }
    ],
    "dbxrefs": [
        "PANC-DB:HPAP-083"
    ],
    "description": "Human pancreas donor SAMN19842612 in the HPAP database",
    "diabetes_duration": "2-3",
    "diabetes_status": [
        "/phenotype-terms/MONDO_0005148/"
    ],
    "diabetes_status_description": "type 2 diabetes",
    "donation_type": "DBD",
    "ethnicities": [
        "African American",
        "Black"
    ],
    "family_history_of_diabetes": "false",
    "genetic_ethnicities": [
        {
            "ethnicity": "African",
            "percentage": 97
        },
        {
            "ethnicity": "Admixed-American",
            "percentage": 3
        }
    ],
    "glucose_loweing_theraphy": [
        "Insulin"
    ],
    "hba1c": 5,
    "hla_typing": [
        "A,23-29,RT-PCR",
        "B,07-45,RT-PCR",
        "Bw4,0-0,RT-PCR",
        "Bw6,1-1,RT-PCR",
        "C,07-16,RT-PCR",
        "DPB1,01:01-17:01,RT-PCR",
        "DQA1,01-05,RT-PCR",
        "DQB1,03:07-05,RT-PCR",
        "DR,01-13,RT-PCR",
        "DR51,0-0,RT-PCR",
        "DR52,52-52,RT-PCR",
        "DR53,0-0,RT-PCR"
    ],
    "hospital_stay": 119,
    "human_donor_identifiers": [
        "PANC-DB:HPAP-083"
    ],
    "lab": {
        "@id": "/labs/klaus-kaestner/",
        "title": "Klaus Kaestner, UPenn"
    },
    "living_donor": false,
    "notes": "other disease states: Hypertension",
    "other_tissues_available": [
        "/sample-terms/UBERON_0002113/",
        "/sample-terms/UBERON_0002107/",
        "/sample-terms/UBERON_0002048/",
        "/sample-terms/UBERON_0001264/",
        "/sample-terms/UBERON_0000948/"
    ],
    "pancreas_tissue_available": true,
    "publication_identifiers": [
        "PMID:31127054",
        "PMID:36206763"
    ],
    "release_timestamp": "2025-01-10T01:41:36.613739+00:00",
    "rrid": "RRID:SAMN19842612",
    "schema_version": "16",
    "sex": "male",
    "status": "released",
    "submitted_by": {
        "@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
        "title": "Ying Sun"
    },
    "submitter_comment": "Meta-data was obtained directly from PANC-DB",
    "summary": "African American, Black male /phenotype-terms/MONDO_0005148/",
    "taxa": "Homo sapiens",
    "url": "https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-083",
    "uuid": "4cc14ab3-5e57-4851-925e-a3f209c45f09",
    "virtual": false
}