Treatment
Title
Treatment
Description
A protein or chemical treatment applied to samples such as lipopolysaccharide, interleukin-2, or leucine.
Required
award, depletion, lab, purpose, treatment_term_name, treatment_type
Identifying Properties
aliases, uuid
Highlight properties with matching names, “title” attributes, or an enum of those properties. Matching properties might be non-submittable.
array[string]
Lab specific identifiers to reference an object.
number
Specific quantity of the applied treatment (used in conjunction with amount_units).
string
A unit for an amount other than those for time or temperature.
linkto
Grant associated with the submission.
boolean
Treatment is depleted.
string
A plain text description of the object.
array[linkto]
Documents that describe the treatment protocol details.
number
Duration indicates the time elapsed between the start and end of the treatment.
string
A unit of time.
linkto
Lab associated with the submission.
string
The lot identifier provided by the originating lab or vendor.
number
Final pH of the solution containing a chemical compound (if applicable)
number
Post treatment time in conjunction with post treatment time units is used to specify the time that has passed between the point when biosamples were removed from the treatment solution before being sampled or treated with the next treatment.
string
A unit of time.
string
The product identifier provided by the originating lab or vendor.
string
The intended purpose for treating the samples; Activation: treatment is known to activate a pathway in the biosample; Agonist: a substance which is known to initiate a physiological response when combined with a receptor; Antagonist: a substance that is known to interfere with or inhibits the physiological action of another; Control: treatment applied to a sample for control purposes; Differentiation: treatment that is applied to convert a less specialized cell to a more specialized cell; De-differentiation: treatment used to reprogram differentiated cells back to less determined cell states; Perturbation: treatment applied to the sample in order to study the effect of its application; Selection: treatment used to affect biosample in a way that can be used to distinguish cells and select for in the downstream steps; Stimulation: treatment applied to stimulate a cellular pathway.
array[linkto]
The originating lab(s) or vendor(s).
string
Additional information specified by the submitter to be displayed as a comment on the portal.
number
The temperature in Celsius to which the sample was exposed
string
A unit of temperature.
string
Ontology identifier describing a component in the treatment.
string
Ontology term describing a component in the treatment that is the principal component affecting the biosample being treated. Examples: interferon gamma, interleukin-4, Fibroblast growth factor 2, 20-hydroxyecdysone, 5-bromouridine etc.
string
The classification of treatment agent that specifies its exact molecular nature. Chemical type refers to (natural or synthetic) organic/inorganic compounds and also includes drugs, while protein type is restricted to active protein biomolecules that are naturally or artifically synthesized via cellular translation mechanism of converting DNA into a protein. Environmental type referes to other external conditions that directly influence biological processes or reactions within a given environment. Example of chemical type: lactate, ethanol,hydrocortisone, LPS etc. Example of protein type: Interferons, interlukin, antibodies, etc. Example of chemical type: stiffness.
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies