Human Donor

Title

Human Donor

Description

A human donor of any biosample, including cell lines. Submission of any sample originating from a human donor requires submission of information about the relevant donor. For example, submission of the donor of K562 is a prerequisite for submission of any K562 cell line samples. The following fields are **required**: `award`, `lab`, `rrid`, `living_donor`, `bmi`, `diabetes_status`, `diabetes_status_description`, and `taxa`. These fields must be included for the schema to be valid. Additionally, the following fields are **desired**: `center_donor_id`, `ethnicities`, `hba1c`, `diabetes_status_hba1c`, `glucose_loweing_theraphy`, `hospital_stay`, `donation_type`, and `cause_of_death`. While these fields are not mandatory, their inclusion is highly recommended for a more comprehensive data submission.

Required

age, award, center_donor_id, lab, living_donor, taxa

Identifying Properties

accession, aliases, alternate_accessions, uuid

Search Schema Properties

Highlight properties with matching names, “title” attributes, or an enum of those properties. Matching properties might be non-submittable.

Include non-submittable properties

boolean

The presence of Autoantibodies against GADA

number

AAB GADA value (unit/ml)

boolean

The presence of Autoantibodies against IA2

number

AAB IA2 value (unit/ml)

boolean

The presence of Autoantibodies against IAA

number

AAB IAA value (unit/ml)

boolean

The presence of Autoantibodies against ZNT8

number

AAB ZNT8 value (unit/ml)

number

Age in years

array[string]

Lab specific identifiers to reference an object.

linkto

Grant associated with the submission.

string

Inferred biological sex derived from genomic data

number

Body mass index (Kg/m2)

number

The concentration of C-Peptide in the blood, a marker used to assess insulin production and pancreatic function

string

The primary medical condition or event that led to the patient’s death

string

Donor center ID identifier for cross-referencing

array[object]

A list of datasets available for the donor, each with tissue and a corresponding link to access the dataset.

array[string]

Identifiers from external resources that may have 1-to-1 or 1-to-many relationships with IGVF donors.

string

A plain text description of the object.

string

Diabetes Duration in years

array[linkto]

Diabetes status T1D,T2D,MODY, etc. MONDO ontology term

string

Description of diabetes status

string

A categorization of diabetes status based on adjusted HbA1C levels, considering factors such as age, race, or other clinical conditions that might influence HbA1C measurements

array[linkto]

Documents that provide additional information (not data file).

string

The type of organ donation, categorized as DCD, NDD, or MAID

array[string]

Self-Reported Ethnicity of the donor.

string

Family History of Diabetes

array[string]

Family History of Diabetes Relationship.

array[object]

Inferred ancestry of the donor from genetic analysis, including optional percentage values for each ethnicity.

array[string]

Details the type of therapy or medication regimen the patient is on to manage blood glucose levels, including oral medications, insulin, or other treatments.

number

The percentage measurement of HbA1c, which reflects the average blood glucose levels over the past 2-3 months. If not available, 'NA'

array[string]

Series of comma-separated values describing HLA types as: class, locus, allele1, allele2, method

number

The total number of hours the patient was hospitalized

linkto

Lab associated with the submission.

boolean

Living Donor

array[linkto]

Tissues obtained from the donor

boolean

Pancreas tissue is available for research or analysis

array[linkto]

A list of associated phenotypic features of the donor.

array[string]

The publication identifiers that provide more information about the object.

array[object]

Familial relations of this donor also in PanKbase .

string

Research Unique Identifier. PanKbase will only take donors with RRID

string

Self-Reported sex of the donor.

string

Additional information specified by the submitter to be displayed as a comment on the portal.

string

The species of the organism.

string

An external resource with additional information.

boolean

Virtual donors are not representing actual human or model organism donors, samples coming from which were used in experiments, but rather capturing metadata about hypothetical donors that the reported analysis results are relevant for.