PKBSM1698XCWE

{
    "@context": "/terms/",
    "@id": "/primary-islet/PKBSM1698XCWE/",
    "@type": [
        "PrimaryIslet",
        "Biosample",
        "Sample",
        "Item"
    ],
    "accession": "PKBSM1698XCWE",
    "age": "unknown",
    "aliases": [
        "joyce-niland:SAMN10861888_bulkIslet_secondaryBiosample_Interferongamma10ngmL_Interleukin1beta0.5ngmL_Tumornecrosisfactoralpha1ngmL24h"
    ],
    "audit": {
        "WARNING": [
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBSM1698XCWE](/primary-islet/PKBSM1698XCWE/) is missing tier 2 field `rrid`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/primary-islet/PKBSM1698XCWE/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBSM1698XCWE](/primary-islet/PKBSM1698XCWE/) is missing tier 2 field `organ_source`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/primary-islet/PKBSM1698XCWE/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBSM1698XCWE](/primary-islet/PKBSM1698XCWE/) is missing tier 2 field `prep_viability`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/primary-islet/PKBSM1698XCWE/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBSM1698XCWE](/primary-islet/PKBSM1698XCWE/) is missing tier 2 field `warm_ischaemia_duration`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/primary-islet/PKBSM1698XCWE/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBSM1698XCWE](/primary-islet/PKBSM1698XCWE/) is missing tier 2 field `hand_picked`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/primary-islet/PKBSM1698XCWE/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBSM1698XCWE](/primary-islet/PKBSM1698XCWE/) is missing tier 2 field `pre_shipment_culture_time`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/primary-islet/PKBSM1698XCWE/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBSM1698XCWE](/primary-islet/PKBSM1698XCWE/) is missing tier 2 field `islet_function_available`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_desired_fields",
                "path": "/primary-islet/PKBSM1698XCWE/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U24DK098085/"
    },
    "biosample_type": "Post-shipment",
    "classifications": [
        "primary islet"
    ],
    "cold_ischaemia_time": -999,
    "creation_timestamp": "2025-10-17T00:39:06.192229+00:00",
    "description": "Post-shipment treatment of islet biosample from human donor SAMN10861888, IFNy 10 ng/mL, IL1b 0.5 ng/mL, TNFa 1 ng/mL for 24 hr",
    "donors": [
        {
            "@id": "/human-donors/PKBDO9989ZHGJ/",
            "accession": "PKBDO9989ZHGJ",
            "age": 58,
            "gender": "Female",
            "summary": "PKBDO9989ZHGJ",
            "taxa": "Homo sapiens"
        }
    ],
    "file_sets": [
        {
            "@id": "/measurement-sets/PKBDS1022XNKA/",
            "accession": "PKBDS1022XNKA",
            "aliases": [
                "pankbase-consortium:bulkIslets_GSE205853_SAMN10861888_Interferongamma10ngmL_Interleukin1beta0.5ngmL_Tumornecrosisfactoralpha1ngmL24h_MeasurementSet"
            ],
            "assay_term": {
                "term_name": "bulk RNA-seq assay"
            },
            "lab": {},
            "status": "released"
        },
        {
            "@id": "/analysis-sets/PKBDS4893QTVY/",
            "accession": "PKBDS4893QTVY",
            "aliases": [
                "pankbase-consortium:bulkIslets_GSE205853_SAMN10861888_Interferongamma10ngmL_Interleukin1beta0.5ngmL_Tumornecrosisfactoralpha1ngmL24h_AnalysisSet"
            ],
            "lab": {},
            "status": "released"
        }
    ],
    "institutional_certificates": [],
    "isolation_center": "SC-ICRC – Southern California Islet Cell Resources Center",
    "lab": {
        "@id": "/labs/joyce-niland/"
    },
    "multiplexed_in": [],
    "origin_of": [],
    "originated_from": "/primary-islet/PKBSM5266QJNB/",
    "parts": [],
    "pooled_in": [],
    "purity": [
        "-"
    ],
    "release_timestamp": "2025-10-27T19:41:12.854294+00:00",
    "sample_terms": [
        {
            "@id": "/sample-terms/UBERON_0000006/",
            "term_name": "islet of Langerhans"
        }
    ],
    "schema_version": "21",
    "sex": "Female",
    "sorted_fractions": [],
    "sources": [
        {
            "@id": "/labs/joyce-niland/"
        }
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
        "title": "Ying Sun"
    },
    "submitter_comment": "From GEO record GSE205853",
    "summary": "islet of Langerhans cell, Female, Homo sapiens treated with 0.5 ng/mL Interleukin-1 beta for 24 hours, 1 ng/mL Tumor necrosis factor alpha for 24 hours, 10 ng/mL Interferon gamma for 24 hours",
    "treatments": [
        {
            "@id": "/treatments/0182f31f-efaf-43c8-a274-b0705fa09cb9/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Treatment of 10 ng/mL Interferon gamma for 24 hours",
            "treatment_type": "protein"
        },
        {
            "@id": "/treatments/336c5c74-71f4-43e0-90b4-f4252273212b/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Treatment of 0.5 ng/mL Interleukin-1 beta for 24 hours",
            "treatment_type": "protein"
        },
        {
            "@id": "/treatments/eb736343-2dac-4daf-907b-bfb553125c3a/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Treatment of 1 ng/mL Tumor necrosis factor alpha for 24 hours",
            "treatment_type": "protein"
        }
    ],
    "uuid": "b70bbbc6-e8ca-4d1e-a32d-cdd3205e7129",
    "virtual": false
}