{
"@context": "/terms/",
"@id": "/measurement-sets/PKBDS6336PTTC/",
"@type": [
"MeasurementSet",
"FileSet",
"Item"
],
"accession": "PKBDS6336PTTC",
"aliases": [
"klaus-kaestner:scRNAseq_IsletCells_HPAP-110"
],
"assay_term": {
"@id": "/assay-terms/OBI_0002631/",
"term_name": "single-cell RNA sequencing assay"
},
"audit": {
"NOT_COMPLIANT": [
{
"category": "missing nih certification",
"detail": "Measurement set [PKBDS6336PTTC](/measurement-sets/PKBDS6336PTTC/) has a sample [PKBSM4218XGLJ](/primary-islet/PKBSM4218XGLJ/) that lacks any `institutional_certificates` issued to the lab that submitted this file set. Measurement sets for mapping assays involving samples with a human origin are expected to link to the relevant institutional certificates issued to a matching lab and award.",
"level": 50,
"level_name": "NOT_COMPLIANT",
"name": "audit_missing_institutional_certification",
"path": "/measurement-sets/PKBDS6336PTTC/"
}
],
"WARNING": [
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO2053KPTA](/human-donors/PKBDO2053KPTA/) is missing tier 2 field `diabetes_status_hba1c`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/human-donors/PKBDO2053KPTA/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO2053KPTA](/human-donors/PKBDO2053KPTA/) is missing tier 2 field `glucose_loweing_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/human-donors/PKBDO2053KPTA/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2053KPTA](/human-donors/PKBDO2053KPTA/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO2053KPTA/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2053KPTA](/human-donors/PKBDO2053KPTA/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO2053KPTA/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2053KPTA](/human-donors/PKBDO2053KPTA/) is missing tier 3 field `biological_sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO2053KPTA/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2053KPTA](/human-donors/PKBDO2053KPTA/) is missing tier 3 field `diabetes_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO2053KPTA/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO2053KPTA](/human-donors/PKBDO2053KPTA/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO2053KPTA/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM4218XGLJ](/primary-islet/PKBSM4218XGLJ/) is missing tier 2 field `warm_ischaemia_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM4218XGLJ/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM4218XGLJ](/primary-islet/PKBSM4218XGLJ/) is missing tier 2 field `pre_shipment_culture_time`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM4218XGLJ/"
},
{
"category": "missing files",
"detail": "Measurement set [PKBDS6336PTTC](/measurement-sets/PKBDS6336PTTC/) has no `files`. File sets are expected to have files.",
"level": 40,
"level_name": "WARNING",
"name": "audit_no_files",
"path": "/measurement-sets/PKBDS6336PTTC/"
},
{
"category": "inconsistent assays",
"detail": "Measurement set [PKBDS6336PTTC](/measurement-sets/PKBDS6336PTTC/) has `assay_term` single-cell RNA sequencing assay, but `preferred_assay_title` scRNA-seq. Measurement sets with a preferred assay title are expected to specify an appropriate assay term.",
"level": 40,
"level_name": "WARNING",
"name": "audit_preferred_assay_title",
"path": "/measurement-sets/PKBDS6336PTTC/"
}
]
},
"award": {
"@id": "/awards/UC4DK112217/",
"contact_pi": {
"@id": "/users/e1c8c91f-3952-45a9-9f56-442627f60c13/",
"title": "Klaus Kaestner"
},
"title": "PENN INTEGRATED HUMAN PANCREAS PROCUREMENT AND ANALYSIS PROGRAM"
},
"collections": [
"HPAP"
],
"control_for": [],
"creation_timestamp": "2024-12-06T00:02:56.580142+00:00",
"donors": [
{
"@id": "/human-donors/PKBDO2053KPTA/",
"accession": "PKBDO2053KPTA",
"aliases": [
"klaus-kaestner:HPAP-110"
],
"sex": "male",
"status": "released",
"taxa": "Homo sapiens"
}
],
"file_set_type": "experimental data",
"files": [],
"input_file_set_for": [
"/analysis-sets/PKBDS8427QUCQ/"
],
"lab": {
"@id": "/labs/klaus-kaestner/",
"title": "Klaus Kaestner, UPenn"
},
"library_construction_platform": [
{
"@id": "/platform-terms/EFO_0008637/",
"term_name": "Illumina NovaSeq 6000"
}
],
"notes": "HPAP-110",
"preferred_assay_title": "scRNA-seq",
"protocols": [
"https://hpap.pmacs.upenn.edu/explore/workflow/islet-molecular-phenotyping-studies?protocol=4"
],
"publication_identifiers": [
"PMID:31127054",
"PMID:36206763"
],
"release_timestamp": "2025-01-10T05:47:14.160881+00:00",
"samples": [
{
"@id": "/primary-islet/PKBSM4218XGLJ/",
"@type": [
"PrimaryIslet",
"Biosample",
"Sample",
"Item"
],
"accession": "PKBSM4218XGLJ",
"aliases": [
"klaus-kaestner:biosample_HPAP-110"
],
"sample_terms": [
{
"@id": "/sample-terms/UBERON_0000006/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"kyle-gaulton:sample_isletofLangerhans"
],
"status": "released",
"summary": "islet of Langerhans",
"term_name": "islet of Langerhans"
}
],
"status": "released",
"summary": "islet of Langerhans cell, male, Homo sapiens",
"taxa": "Homo sapiens"
}
],
"schema_version": "17",
"sequencing_library_types": [
"polyA enriched"
],
"status": "released",
"submitted_by": {
"@id": "/users/7e95dcd6-9c35-4082-9c53-09d14c5752be/",
"title": "Parul Kudtarkar"
},
"summary": "single-cell RNA sequencing assay (scRNA-seq)",
"uuid": "ea668b46-8949-4189-94ab-bd3a4c2ac45c"
}