PKBDO9644DBMV
PKBDO9644DBMV
released
Clinical summary
Diabetes status
Type 1 Diabetes
Age (y)
12
Age group
0-12
BMI
18.5
Height (cm)
—
Weight (kg)
—
HbA1c %
13.3
C-Peptide (ng/ml)
2.2
Diabetes duration
—
AAB summary
GADA+, IA2+, ZNT8+
AAB count
3
Demographics
- Age (y)
- 12
- Age group
- 0-12
- Pediatric
- Yes
- Gender
- Female
- Genetic Sex
- Female
- Sex discordant
- No
- Ethnicity
- White
- Predicted genetic ancestry
- European (99%), African (1%)
- Dominant genetic ancestry
- European
Additional clinical
- Diabetes (ontology)
- T1D stage
- Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
- HbA1c-derived diabetes status
- Diabetes
- Label vs HbA1c discordant
- No
- Tier 1 complete
- Yes
- Family history of diabetes
- FALSE
- Living donor
- No
- Cause of death
- Anoxia
- Donation type
- Donation after brain death
- Hospital stay (h)
- 140
Autoantibodies
- Summary
- GADA+, IA2+, ZNT8+
- Any positive
- Yes
- Tested
- Yes
- Positive count
- 3
GADAPositive
27 unit/ml
IAANegative
-0.001 unit/ml
IA2Positive
139 unit/ml
ZNT8Positive
0.116 unit/ml
HLA typing
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 01:01 | 01:1 | NGS |
| A | 1 | 2 | RT-PCR |
| B | 57 | 57 | RT-PCR |
| B | 57:01 | — | NGS |
| Bw4 | 1 | 1 | RT-PCR |
| Bw6 | 0 | 0 | RT-PCR |
| C | 06 | 06 | RT-PCR |
| C | 06:02 | — | NGS |
| DPA1 | 01:03 | — | NGS |
| DPB1 | 04:01 | — | NGS |
| DPB1 | 04:01 | 04:01 | RT-PCR |
| DQA1 | 05 | 05 | RT-PCR |
| DQA1 | 05:01 | — | NGS |
| DQB1 | 02:01 | — | NGS |
| DQB1 | 2 | 2 | RT-PCR |
| DR | 03:01 | 03:01 | RT-PCR |
| DR51 | 0 | — | RT-PCR |
| DR52 | 03:01 | 03:01 | RT-PCR |
| DR53 | 0 | — | RT-PCR |
| DRB1 | 03:01 | — | NGS |
| DRB3 | 01:01 | — | NGS |
| DRB4 | — | — | NGS |
| DRB5 | — | — | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, RNAseq, scRNAseq, snATACseq, Function, Histology, CODEX, imaging_mass_spec, scMultiome, TCRseq, BCRseq, Flow_cytometry
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
Pancreas
Spleen
scMultiomeAccess dataset
TCRseqAccess dataset
BCRseqAccess dataset
Flow_cytometryAccess dataset
histologyAccess dataset
Lymph
Peripheral_blood
Flow_cytometryAccess dataset
Supplementary
HPAP
PANC-DB:HPAP-084
- Pancreas tissue available
- Yes
- Other tissues
External resources
PANC-DB:HPAP-084
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
