PKBDO9485JKVO
PKBDO9485JKVO
released
Clinical summary
Diabetes status
Control Without Diabetes
Age (y)
21
Age group
18-39
BMI
28.99
Height (cm)
—
Weight (kg)
—
HbA1c %
5.1
C-Peptide (ng/ml)
3.79
Diabetes duration
—
AAB summary
GADA+
AAB count
1
Demographics
- Age (y)
- 21
- Age group
- 18-39
- Pediatric
- No
- Gender
- Female
- Genetic Sex
- Female
- Sex discordant
- No
- Ethnicity
- Hispanic
- Predicted genetic ancestry
- Admixed-American (99%), South-Asian (1%)
- Dominant genetic ancestry
- Admixed-American
Additional clinical
- Diabetes (ontology)
- No ontology term
- T1D stage
- At-risk: single or transient autoantibody, normal glucose level
- HbA1c-derived diabetes status
- Normal
- Label vs HbA1c discordant
- No
- Tier 1 complete
- No
- Family history of diabetes
- TRUE
- Family history relationship
- Maternal_grandparent, Paternal_grandparent
- Living donor
- No
- Cause of death
- Anoxia
- Donation type
- Donation after brain death
- Hospital stay (h)
- 144
Autoantibodies
- Summary
- GADA+
- Any positive
- Yes
- Tested
- Yes
- Positive count
- 1
GADAPositive
203 unit/ml
1
IAANegative
0.003 unit/ml
IA2Negative
0 unit/ml
ZNT8Negative
0.004 unit/ml
HLA typing
Status: DR4/X
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 24 | 24 | RT-PCR |
| A | 24:02 | 24:25 | NGS |
| B | 48 | 55 | RT-PCR |
| B | 48:01 | 55:01 | NGS |
| Bw4 | — | — | RT-PCR |
| Bw6 | 1 | 1 | RT-PCR |
| C | 01 | 08 | RT-PCR |
| C | 01:02 | 08:01 | NGS |
| DPA1 | 01:03 | — | NGS |
| DPB1 | 04 | 04:02:01G | RT-PCR |
| DPB1 | 04:01 | 04:02 | NGS |
| DQA1 | 01 | 03 | RT-PCR |
| DQA1 | 01:02 | 03:01 | NGS |
| DQB1 | 03:02 | 06:09 | NGS |
| DQB1 | 03:02 | 06 | RT-PCR |
| DR | 4 | 13 | RT-PCR |
| DR51 | — | — | RT-PCR |
| DR52 | — | 03 | RT-PCR |
| DR53 | 01 | — | RT-PCR |
| DRB1 | 13:02 | 04:04 | NGS |
| DRB3 | 03:01 | — | NGS |
| DRB4 | — | 01:03 | NGS |
| DRB5 | — | — | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, scRNAseq, snATACseq, Function, Imaging, CyTof, Histology, imaging_mass_spec, TCRseq, BCRseq, Flow_cytometry
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
scRNAseqAccess dataset
snATACseqAccess dataset
FunctionAccess dataset
ImagingAccess dataset
CyTofAccess dataset
Pancreas
histologyAccess dataset
imaging_mass_specAccess dataset
Spleen
Lymph
Flow_cytometryAccess dataset
histologyAccess dataset
Peripheral_blood
Flow_cytometryAccess dataset
Supplementary
HPAP
PANC-DB:HPAP-050
- Pancreas tissue available
- Yes
- Other tissues
Publication data
External resources
PANC-DB:HPAP-050
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
