PKBDO7633ARWR
PKBDO7633ARWR
released
Clinical summary
Diabetes status
Type 1 Diabetes
Age (y)
13
Age group
13-17
BMI
21.4
Height (cm)
—
Weight (kg)
—
HbA1c %
—
C-Peptide (ng/ml)
0.02
Diabetes duration
7
AAB summary
IAA+
AAB count
1
Demographics
- Age (y)
- 13
- Age group
- 13-17
- Pediatric
- Yes
- Gender
- Female
- Genetic Sex
- Female
- Sex discordant
- No
- Ethnicity
- White
- Predicted genetic ancestry
- European (97%), Admixed-American (3%)
- Dominant genetic ancestry
- European
Additional clinical
- Diabetes (ontology)
- T1D stage
- Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
- Tier 1 complete
- Yes
- Family history of diabetes
- TRUE
- Living donor
- No
- Cause of death
- Anoxia
- Donation type
- Donation after brain death
- Hospital stay (h)
- 115
- Medication
- Insulin
Autoantibodies
- Summary
- IAA+
- Any positive
- Yes
- Tested
- Yes
- Positive count
- 1
GADANegative
0 unit/ml
IAAPositive
0.487 unit/ml
1
IA2Negative
0 unit/ml
ZNT8Negative
-0.008 unit/ml
HLA typing
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 02:01 | 03:01 | NGS |
| A | 2 | 3 | RT-PCR |
| B | 07:02 | 44:02 | NGS |
| B | 7 | 44 | RT-PCR |
| Bw4 | 1 | 1 | RT-PCR |
| Bw6 | 1 | 1 | RT-PCR |
| C | 05:01 | 07:02 | NGS |
| C | 5 | 7 | RT-PCR |
| DPA1 | 01:03 | 02:01 | NGS |
| DPB1 | 06:01 | 10:01 | NGS |
| DPB1 | 06:01 | 10:01 | RT-PCR |
| DQA1 | 01 | 03 | RT-PCR |
| DQA1 | 01:01 | 03:03 | NGS |
| DQB1 | 03:02 | 05:01 | NGS |
| DQB1 | 5 | 8 | RT-PCR |
| DR | 1 | 4 | RT-PCR |
| DR51 | 0 | 0 | RT-PCR |
| DR52 | 0 | 0 | RT-PCR |
| DR53 | 53 | — | RT-PCR |
| DRB1 | 01:01 | 04:01 | NGS |
| DRB3 | — | — | NGS |
| DRB4 | — | 01:03 | NGS |
| DRB5 | — | — | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, scRNAseq, Function, Imaging, CyTof, Histology, imaging_mass_spec, TCRseq, BCRseq, Flow_cytometry, CITEseq
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph, Thymus, Peripheral_blood
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
Pancreas
histologyAccess dataset
imaging_mass_specAccess dataset
Spleen
Lymph
Thymus
histologyAccess dataset
Peripheral_blood
Flow_cytometryAccess dataset
Supplementary
HPAP
PANC-DB:HPAP-021
- Pancreas tissue available
- Yes
- Other tissues
External resources
PANC-DB:HPAP-021
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
