released

PKBDO6659SMJN

released

RRID RRID:SAMN19842590Program Donor ID SAMN19842590

Clinical summary

Diabetes status

Type 2 Diabetes

Age (y)

Age group

40-64

BMI

38.27

Height (cm)

—

Weight (kg)

—

HbA1c %

5.9

C-Peptide (ng/ml)

1.14

Diabetes duration

—

AAB summary

none positive

AAB count

Demographics

Age (y): 59
Age group: 40-64
Pediatric: No
Gender: Female
Genetic Sex: Female
Sex discordant: No
Ethnicity: African American
Predicted genetic ancestry: African (94%), Admixed-American (3%), South-Asian (3%)
Dominant genetic ancestry: African

Additional clinical

Diabetes (ontology): MONDO:0005148
T1D stage: No sufficient information to derive
HbA1c-derived diabetes status: Prediabetes
Label vs HbA1c discordant: No
Tier 1 complete: Yes
Family history of diabetes: FALSE
Living donor: No
Cause of death: Cerebrovascular/Stroke
Donation type: Donation after brain death
Hospital stay (h): 109
Medication: Metformin,Ozempic

Autoantibodies

Summary: none positive
Any positive: No
Tested: Yes
Positive count: 0

GADANegative

0 unit/ml

IAANegative

-0.002 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

-0.015 unit/ml

HLA typing

Status: X/X

Locus	Allele 1	Allele 2	Method
A	30	33	RT-PCR
B	71	49	RT-PCR
Bw4	1	1	RT-PCR
Bw6	1	1	RT-PCR
C	10	07	RT-PCR
DPB1	—	—	RT-PCR
DQA1	—	—	RT-PCR
DQB1	—	—	RT-PCR
DR	8	9	RT-PCR
DR51	0	0	RT-PCR
DR52	0	0	RT-PCR
DR53	4:01	0	RT-PCR

Data available

Datasets: Genotyping, HLA_typing, scRNAseq, snATACseq, Function, Imaging, CyTof, Histology, imaging_mass_spec
Tissues: unspecified, Islet, Pancreas, Spleen, Lymph

imaging_mass_specAccess dataset

Spleen

histologyAccess dataset

Lymph

histologyAccess dataset

Supplementary

HPAP

Identifiers

PANC-DB:HPAP-061

Pancreas tissue available: Yes
Other tissues: UBERON:0002107, UBERON:0001264

Publication identifiers

PMID:31127054, PMID:36206763

Description

Human pancreas donor SAMN19842590 in the HPAP database

External resources

PANC-DB:HPAP-061

URL

https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-061