released

PKBDO6479CXUF

released

RRID RRID:SAMN19776480Program Donor ID SAMN19776480

Clinical summary

Diabetes status

Control Without Diabetes

BMI

37.2

HbA1c %

5.4

C-Peptide (ng/ml)

6.15

Diabetes duration

—

Demographics

Age (y): 29
Gender: Male
Genetic Sex: Male
Ethnicity: White
Predicted genetic ancestry: European (87%), African (5%), East-Asian (4%), Admixed-American (4%)

Additional clinical

Diabetes (ontology): No ontology term
T1D stage: At-risk: single or transient autoantibody, normal glucose level
Derived diabetes status: Normal
Family history of diabetes: TRUE
Family history relationship: Aunt, Uncle
Living donor: No
Cause of death: Head Trauma
Donation type: Donation after brain death
Hospital stay (h): 81

Autoantibodies

GADAPositive

412 unit/ml

1

IAANegative

0.001 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

0.005 unit/ml

HLA typing

Locus	Allele 1	Allele 2	Method
A	24	32	RT-PCR
A	24:2	32:01	NGS
B	07:02	49:01	NGS
B	7	49	RT-PCR
Bw4	1	1	RT-PCR
Bw6	1	1	RT-PCR
C	07	07	RT-PCR
C	07:01	07:02	NGS
DPA1	01:03	02:01	NGS
DPB1	04:01	13:01	NGS
DPB1	04:01	13:01	RT-PCR
DQA1	02	05	RT-PCR
DQA1	02:01	05:05	NGS
DQB1	03:03	03:19	NGS
DQB1	7	9	RT-PCR
DR	7	11	RT-PCR
DR51	0	0	RT-PCR
DR52	0	52	RT-PCR
DR53	0	0	RT-PCR
DRB1	11:02	07:01	NGS
DRB3	02:02	—	NGS
DRB4	—	01:03N	NGS
DRB5	—	—	NGS

Data available

Genetics

GenotypingAccess dataset

HLA_typingAccess dataset

Islet

RNAseqAccess dataset

scRNAseqAccess dataset

snATACseqAccess dataset

FunctionAccess dataset

ImagingAccess dataset

CyTofAccess dataset

WGBSAccess dataset

Pancreas

histologyAccess dataset

imaging_mass_specAccess dataset

Spleen

TCRseqAccess dataset

BCRseqAccess dataset

Flow_cytometryAccess dataset

histologyAccess dataset

Lymph

Flow_cytometryAccess dataset

histologyAccess dataset

Peripheral_blood

Flow_cytometryAccess dataset

Supplementary

HPAP

Identifiers

PANC-DB:HPAP-049

Pancreas tissue available: Yes
Other tissues: UBERON:0002107, UBERON:0002168, UBERON:0000948, UBERON:0002113, UBERON:0001264

Publication data

PMID:35228745, PMID:37582230

Publication identifiers

PMID:31127054, PMID:36206763

Description

Human pancreas donor SAMN19776480 in the HPAP database

External resources

PANC-DB:HPAP-049

URL

https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-049

Attribution