released

PKBDO5844WPGY

released

RRID RRID:SAMN19776455Program Donor ID SAMN19776455

Clinical summary

Diabetes status

Control Without Diabetes

BMI

24.3

HbA1c %

5.5

C-Peptide (ng/ml)

5.6

Diabetes duration

—

Demographics

Age (y): 18
Gender: Male
Genetic Sex: Male
Ethnicity: White
Predicted genetic ancestry: European (95%), East-Asian (2%), African (2%), Admixed-American (1%)

Additional clinical

Diabetes (ontology): No ontology term
T1D stage: At-risk: single or transient autoantibody, normal glucose level
Derived diabetes status: Normal
Family history of diabetes: TRUE
Family history relationship: Maternal_grandmother
Living donor: No
Cause of death: Head Trauma
Donation type: Donation after circulatory death
Hospital stay (h): 33

Autoantibodies

GADAPositive

203 unit/ml

1

IAANegative

0 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

0 unit/ml

HLA typing

Locus	Allele 1	Allele 2	Method
A	02:01	—	NGS
A	2	—	RT-PCR
B	40:01	51:01	NGS
B	51	60	RT-PCR
Bw4	1	1	RT-PCR
Bw6	1	1	RT-PCR
C	02	10	RT-PCR
C	03:04	02:02	NGS
DPA1	01:03	—	NGS
DPB1	03:01	—	NGS
DPB1	03:01	—	RT-PCR
DQA1	04	05	RT-PCR
DQA1	04:01	05:05	NGS
DQB1	04:02	03:01	NGS
DQB1	4	7	RT-PCR
DR	8	11	RT-PCR
DR51	0	0	RT-PCR
DR52	0	0	RT-PCR
DR53	0	0	RT-PCR
DRB1	08:01	11:01	NGS
DRB3	—	02:02	NGS
DRB4	—	—	NGS
DRB5	—	—	NGS

Data available

Genetics

GenotypingAccess dataset

HLA_typingAccess dataset

Islet

scRNAseqAccess dataset

ATAC-seqAccess dataset

FunctionAccess dataset

CyTofAccess dataset

Pancreas

histologyAccess dataset

CODEXAccess dataset

imaging_mass_specAccess dataset

Spleen

scMultiomeAccess dataset

TCRseqAccess dataset

BCRseqAccess dataset

Flow_cytometryAccess dataset

histologyAccess dataset

Lymph

scMultiomeAccess dataset

Flow_cytometryAccess dataset

histologyAccess dataset

Peripheral_blood

Flow_cytometryAccess dataset

Supplementary

HPAP

Identifiers

PANC-DB:HPAP-024

Pancreas tissue available: Yes
Other tissues: UBERON:0002048, UBERON:0002113, UBERON:0001264

Publication data

PMID:35228745, PMID:37582230

Publication identifiers

PMID:31127054, PMID:36206763

Description

Human pancreas donor SAMN19776455 in the HPAP database

External resources

PANC-DB:HPAP-024

URL

https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-024

Attribution