released

PKBDO5375SZLV

released

RRID RRID:SAMN19763626Program Donor ID SAMN19763626

Clinical summary

Diabetes status

Type 1 Diabetes

Age (y)

Age group

18-39

BMI

16.4

Height (cm)

—

Weight (kg)

—

HbA1c %

9.8

C-Peptide (ng/ml)

0.51

Diabetes duration

AAB summary

none positive

AAB count

Age (y): 26
Age group: 18-39
Pediatric: No
Gender: Male
Genetic Sex: Male
Sex discordant: No
Ethnicity: Hispanic
Predicted genetic ancestry: Admixed-American (88%), African (5%), South-Asian (7%)
Dominant genetic ancestry: Admixed-American

Diabetes (ontology): MONDO:0005147
T1D stage: Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
HbA1c-derived diabetes status: Diabetes
Label vs HbA1c discordant: No
Tier 1 complete: Yes
Family history of diabetes: TRUE
Family history relationship: Mother
Living donor: No
Cause of death: Anoxia
Donation type: Donation after brain death
Hospital stay (h): 146
Medication: Insulin

GADANegative

0 unit/ml

IAANegative

0.003 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

0 unit/ml

Locus	Allele 1	Allele 2	Method
A	02:01	24:02	NGS
A	02:01	24:02	SSO
A	2	24	RT-PCR
B	35	41	RT-PCR
B	35:17	41:01	NGS
B	35:17	41:01	SSO
Bw4	0	—	RT-PCR
Bw6	1	—	RT-PCR
C	04:01	17:01	NGS
C	04:01	17:01	SSO
C	4	17	RT-PCR
DPA1	01:03	—	NGS
DPB1	02:01	04:02	NGS
DPB1	02:01	04:02	RT-PCR
DQA1	01:02	03:01	NGS
DQA1	1	3	RT-PCR
DQB1	03:02	06:04	NGS
DQB1	8	6	RT-PCR
DR	4	13	RT-PCR
DR51	0	—	RT-PCR
DR52	1	—	RT-PCR
DR53	1	—	RT-PCR
DRB1	13:02	04:08	NGS
DRB3	03:01	—	NGS
DRB4	—	01:03	NGS

Datasets: Genotyping, HLA_typing, RNAseq, Function, Imaging, Morphology, CyTof, WGBS, Histology, imaging_mass_spec, BCRseq
Tissues: unspecified, Islet, Pancreas, Spleen, Lymph