released

PKBDO5081ZNPY

released

RRID RRID:SAMN19776476Program Donor ID SAMN19776476

Clinical summary

Diabetes status

Control Without Diabetes

Age (y)

27

Age group

18-39

BMI

26.2

Height (cm)

—

Weight (kg)

—

HbA1c %

5.2

C-Peptide (ng/ml)

1.7

Diabetes duration

—

AAB summary

GADA+

AAB count

1

Demographics

Age (y): 27
Age group: 18-39
Pediatric: No
Gender: Female
Genetic Sex: -
Ethnicity: White
Predicted genetic ancestry: European (99%), East-Asian (1%)
Dominant genetic ancestry: European

Additional clinical

Diabetes (ontology): No ontology term
T1D stage: At-risk: single or transient autoantibody, normal glucose level
HbA1c-derived diabetes status: Normal
Label vs HbA1c discordant: No
Tier 1 complete: No
Family history of diabetes: -
Living donor: No
Cause of death: Anoxia
Donation type: Donation after brain death
Hospital stay (h): 120

Autoantibodies

Summary: GADA+
Any positive: Yes
Tested: Yes
Positive count: 1

GADAPositive

321 unit/ml

1

IAANegative

0.003 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

0.004 unit/ml

HLA typing

Locus	Allele 1	Allele 2	Method
A	01:01	02:01	NGS
A	1	2	RT-PCR
B	08:01	40:01	NGS
B	8	60	RT-PCR
Bw4	0	0	RT-PCR
Bw6	1	1	RT-PCR
C	03:04	07:01	NGS
C	10	07	RT-PCR
DPA1	01:03	—	NGS
DPB1	03:01	04:01	NGS
DPB1	03:01	04:01	RT-PCR
DQA1	05	05	RT-PCR
DQA1	05:01	—	NGS
DQB1	02:01	—	NGS
DQB1	2	2	RT-PCR
DR	17	17	RT-PCR
DR51	0	—	RT-PCR
DR52	52	—	RT-PCR
DR53	0	—	RT-PCR
DRB1	03:01	—	NGS
DRB3	01:01	—	NGS
DRB4	—	—	NGS
DRB5	—	—	NGS

Data available

Datasets: Genotyping, HLA_typing, RNAseq, scRNAseq, ATAC-seq, snATACseq, Function, Imaging, CyTof, WGBS, Histology, CODEX, imaging_mass_spec, scMultiome, TCRseq, BCRseq, CITEseq, Flow_cytometry
Tissues: unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood

Genetics

GenotypingAccess dataset

HLA_typingAccess dataset

Islet

RNAseqAccess dataset

scRNAseqAccess dataset

ATAC-seqAccess dataset

snATACseqAccess dataset

FunctionAccess dataset

ImagingAccess dataset

CyTofAccess dataset

WGBSAccess dataset

Pancreas

histologyAccess dataset

CODEXAccess dataset

imaging_mass_specAccess dataset

Spleen

scMultiomeAccess dataset

TCRseqAccess dataset

BCRseqAccess dataset

CITEseqAccess dataset

Flow_cytometryAccess dataset

histologyAccess dataset

Lymph

scMultiomeAccess dataset

CITEseqAccess dataset

Flow_cytometryAccess dataset

histologyAccess dataset

Peripheral_blood

Flow_cytometryAccess dataset

Supplementary

HPAP

Identifiers

PANC-DB:HPAP-045

Pancreas tissue available: Yes
Other tissues: UBERON:0002048, UBERON:0002107, UBERON:0000948, UBERON:0002113, UBERON:0001264

Publication data

PMID:35228745, PMID:37582230

Publication identifiers

PMID:31127054, PMID:36206763

Description

Human pancreas donor SAMN19776476 in the HPAP database

External resources

PANC-DB:HPAP-045

URL

https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-045

Attribution