released

PKBDO4608NBMG

released

RRID RRID:SAMN19776474Program Donor ID SAMN19776474

Clinical summary

Diabetes status

Control Without Diabetes

Age (y)

Age group

13-17

BMI

24.07

Height (cm)

—

Weight (kg)

—

HbA1c %

5.9

C-Peptide (ng/ml)

3.19

Diabetes duration

—

AAB summary

IA2+, ZNT8+

AAB count

Diabetes (ontology): No ontology term
T1D stage: Stage 2: two or more autoantibodies, dysglycemia (e.g., HbA1c ≥ 5.7%)
HbA1c-derived diabetes status: Prediabetes
Label vs HbA1c discordant: No
Tier 1 complete: No
Family history of diabetes: TRUE
Family history relationship: Grandmother
Living donor: No
Cause of death: Head Trauma
Donation type: Donation after circulatory death
Hospital stay (h): 195

GADANegative

0 unit/ml

IAANegative

0.001 unit/ml

IA2Positive

155 unit/ml

ZNT8Positive

0.09 unit/ml

Locus	Allele 1	Allele 2	Method
A	24	32	RT-PCR
A	24:02	32:103	NGS
B	35	39	RT-PCR
B	35:02	39:06	NGS
Bw4	0	0	RT-PCR
Bw6	1	1	RT-PCR
C	04	07	RT-PCR
C	04:01	07:02	NGS
DPA1	01:03	—	NGS
DPB1	02:01	04:02	NGS
DPB1	02:01	04:02	RT-PCR
DQA1	05	05	RT-PCR
DQA1	05:03	05:05	NGS
DQB1	03:01	—	NGS
DQB1	7	7	RT-PCR
DR	11	14	RT-PCR
DR51	0	—	RT-PCR
DR52	52	52	RT-PCR
DR53	0	—	RT-PCR
DRB1	11:04	14:06	NGS
DRB3	01:01	02:02	NGS
DRB4	—	—	NGS
DRB5	—	—	NGS

Datasets: Genotyping, HLA_typing, scRNAseq, snATACseq, Function, Imaging, CyTof, Histology, imaging_mass_spec, TCRseq, BCRseq, Flow_cytometry
Tissues: unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood