PKBDO4605VQMH
PKBDO4605VQMH
released
Clinical summary
Diabetes status
Type 1 Diabetes
Age (y)
24
Age group
18-39
BMI
16.98
Height (cm)
—
Weight (kg)
—
HbA1c %
13
C-Peptide (ng/ml)
0.25
Diabetes duration
—
AAB summary
ZNT8+
AAB count
1
Demographics
- Age (y)
- 24
- Age group
- 18-39
- Pediatric
- No
- Gender
- Male
- Genetic Sex
- Male
- Sex discordant
- No
- Ethnicity
- African American
- Predicted genetic ancestry
- African (98%), European (1%), South-Asian (1%)
- Dominant genetic ancestry
- African
Additional clinical
- Diabetes (ontology)
- T1D stage
- Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
- HbA1c-derived diabetes status
- Diabetes
- Label vs HbA1c discordant
- No
- Tier 1 complete
- Yes
- Family history of diabetes
- TRUE
- Family history relationship
- Maternal_grandaunt, Uncle
- Living donor
- No
- Cause of death
- Anoxia
- Donation type
- Donation after brain death
- Hospital stay (h)
- 158
Autoantibodies
- Summary
- ZNT8+
- Any positive
- Yes
- Tested
- Yes
- Positive count
- 1
GADANegative
0 unit/ml
IAANegative
-0.002 unit/ml
IA2Negative
0 unit/ml
ZNT8Positive
0.027 unit/ml
1
HLA typing
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 02:01 | 34:02 | NGS |
| A | 2 | 34 | RT-PCR |
| B | 15:31 | 58:02 | NGS |
| B | 58 | 75 | RT-PCR |
| Bw4 | 1 | 1 | RT-PCR |
| Bw6 | 1 | 1 | RT-PCR |
| C | 06 | 16 | RT-PCR |
| C | 06:02 | 16:01 | NGS |
| DPA1 | 01:03 | 02:01 | NGS |
| DPB1 | 01:01 | 18:01 | NGS |
| DPB1 | 01:01 | 18:01 | RT-PCR |
| DQA1 | 01 | 05 | RT-PCR |
| DQA1 | 01:01 | 05:01 | NGS |
| DQB1 | 02:01 | 05:01 | NGS |
| DQB1 | 2 | 5 | RT-PCR |
| DR | 1 | 17 | RT-PCR |
| DR51 | 0 | 0 | RT-PCR |
| DR52 | 52 | — | RT-PCR |
| DR53 | 0 | 0 | RT-PCR |
| DRB1 | 03:01 | 01:02 | NGS |
| DRB3 | 02:02 | — | NGS |
| DRB4 | — | — | NGS |
| DRB5 | — | — | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, RNAseq, scRNAseq, ATAC-seq, snATACseq, Function, Imaging, CyTof, WGBS, Histology, CODEX, imaging_mass_spec, TCRseq, BCRseq, Flow_cytometry
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
RNAseqAccess dataset
scRNAseqAccess dataset
ATAC-seqAccess dataset
snATACseqAccess dataset
FunctionAccess dataset
ImagingAccess dataset
CyTofAccess dataset
WGBSAccess dataset
Pancreas
Spleen
Lymph
histologyAccess dataset
Peripheral_blood
Flow_cytometryAccess dataset
Supplementary
HPAP
PANC-DB:HPAP-064
- Pancreas tissue available
- Yes
- Other tissues
External resources
PANC-DB:HPAP-064
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
