PKBDO3120YDKP
PKBDO3120YDKP
released
Clinical summary
Diabetes status
Type 1 Diabetes
Age (y)
9
Age group
0-12
BMI
15.92
Height (cm)
—
Weight (kg)
—
HbA1c %
11.1
C-Peptide (ng/ml)
0.06
Diabetes duration
—
AAB summary
ZNT8+
AAB count
1
Demographics
- Age (y)
- 9
- Age group
- 0-12
- Pediatric
- Yes
- Gender
- Male
- Genetic Sex
- Male
- Sex discordant
- No
- Ethnicity
- White
- Predicted genetic ancestry
- European (99%), Admixed-American (1%)
- Dominant genetic ancestry
- European
Additional clinical
- Diabetes (ontology)
- T1D stage
- Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
- HbA1c-derived diabetes status
- Diabetes
- Label vs HbA1c discordant
- No
- Tier 1 complete
- Yes
- Family history of diabetes
- TRUE
- Family history relationship
- Maternal_grandfather
- Living donor
- No
- Cause of death
- Anoxia
- Donation type
- Donation after brain death
- Hospital stay (h)
- 119
- Medication
- No treatment
Autoantibodies
- Summary
- ZNT8+
- Any positive
- Yes
- Tested
- Yes
- Positive count
- 1
GADANegative
0 unit/ml
IAANegative
0 unit/ml
IA2Negative
0 unit/ml
ZNT8Positive
0.137 unit/ml
1
HLA typing
Status: DR3/X
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 02:01 | 31:01 | NGS |
| A | 2 | 31 | RT-PCR |
| B | 18 | 14 | RT-PCR |
| B | 18:01 | 44:02 | NGS |
| Bw4 | 1 | 1 | RT-PCR |
| Bw6 | 1 | 1 | RT-PCR |
| C | 05 | 07 | RT-PCR |
| C | 05:01 | 07:01 | NGS |
| DPA1 | 01:03 | 02:01 | NGS |
| DPB1 | 01:01 | 02:01 | NGS |
| DPB1 | 01:01 | 02:01 | RT-PCR |
| DQA1 | 04 | 05 | RT-PCR |
| DQA1 | 04:01 | 05:01 | NGS |
| DQB1 | 02:01 | 04:02 | NGS |
| DQB1 | 2 | 4 | RT-PCR |
| DR | 17 | 8 | RT-PCR |
| DR51 | 0 | 0 | RT-PCR |
| DR52 | 52 | 0 | RT-PCR |
| DR53 | 0 | 0 | RT-PCR |
| DRB1 | 03:01 | 08:01 | NGS |
| DRB3 | 01:01 | — | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, scRNAseq, Function, Imaging, CyTof, Histology, imaging_mass_spec, scMultiome, snATACseq, TCRseq, BCRseq, Flow_cytometry
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
Pancreas
histologyAccess dataset
imaging_mass_specAccess dataset
Spleen
scMultiomeAccess dataset
TCRseqAccess dataset
BCRseqAccess dataset
Flow_cytometryAccess dataset
histologyAccess dataset
Lymph
Peripheral_blood
Flow_cytometryAccess dataset
Supplementary
HPAP
PANC-DB:HPAP-113
- Pancreas tissue available
- Yes
- Other tissues
External resources
PANC-DB:HPAP-113
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
