PKBDO2731APWI
PKBDO2731APWI
released
Clinical summary
Diabetes status
Type 1 Diabetes
Age (y)
4
Age group
0-12
BMI
17.3
Height (cm)
—
Weight (kg)
—
HbA1c %
9.8
C-Peptide (ng/ml)
0.3
Diabetes duration
3
AAB summary
none positive
AAB count
0
Demographics
- Age (y)
- 4
- Age group
- 0-12
- Pediatric
- Yes
- Gender
- Male
- Genetic Sex
- Male
- Sex discordant
- No
- Ethnicity
- White
- Predicted genetic ancestry
- European (99%), African (1%)
- Dominant genetic ancestry
- European
Additional clinical
- Diabetes (ontology)
- T1D stage
- Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
- HbA1c-derived diabetes status
- Diabetes
- Label vs HbA1c discordant
- No
- Tier 1 complete
- Yes
- Family history of diabetes
- TRUE
- Family history relationship
- Paternal_grandmother
- Living donor
- No
- Cause of death
- DKA
- Donation type
- Donation after brain death
- Hospital stay (h)
- 99
- Medication
- Insulin
Autoantibodies
- Summary
- none positive
- Any positive
- No
- Tested
- Yes
- Positive count
- 0
GADANegative
0 unit/ml
IAANegative
0 unit/ml
IA2Negative
0 unit/ml
ZNT8Negative
0 unit/ml
HLA typing
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 02:01 | 30:02 | NGS |
| A | 2 | 30 | RT-PCR |
| B | 18 | 60 | RT-PCR |
| B | 18:01 | 40:01 | NGS |
| C | 03:04 | 05:01 | NGS |
| C | 10 | 05 | RT-PCR |
| DPA1 | 01:03 | — | NGS |
| DPB1 | 02:02 | 03:01 | NGS |
| DPB1 | 02:02 | 03:01 | RT-PCR |
| DQA1 | 03 | 05 | RT-PCR |
| DQA1 | 03:01 | 05:01 | NGS |
| DQB1 | 02:01 | 03:02 | NGS |
| DQB1 | 2 | 8 | RT-PCR |
| DR | 4 | 17 | RT-PCR |
| DR51 | 0 | — | RT-PCR |
| DR52 | 52 | — | RT-PCR |
| DR53 | 53 | — | RT-PCR |
| DRB1 | 03:01 | 04:04 | NGS |
| DRB3 | 02:02 | — | NGS |
| DRB4 | — | 01:03 | NGS |
| DRB5 | — | — | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, scRNAseq, CyTof, Histology, imaging_mass_spec, scMultiome, snATACseq, TCRseq, BCRseq, Flow_cytometry
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
scRNAseqAccess dataset
CyTofAccess dataset
Pancreas
histologyAccess dataset
imaging_mass_specAccess dataset
Spleen
scMultiomeAccess dataset
TCRseqAccess dataset
BCRseqAccess dataset
Flow_cytometryAccess dataset
histologyAccess dataset
Lymph
Supplementary
HPAP
PANC-DB:HPAP-028
- Pancreas tissue available
- Yes
- Other tissues
External resources
PANC-DB:HPAP-028
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
