released

PKBDO2442ZYVY

released

RRID RRID:SAMN25600004Program Donor ID SAMN25600004

Clinical summary

Diabetes status

Type 2 Diabetes

Age (y)

Age group

40-64

BMI

Height (cm)

—

Weight (kg)

—

HbA1c %

10.8

C-Peptide (ng/ml)

2.24

Diabetes duration

—

AAB summary

GADA+

AAB count

Demographics

Age (y): 42
Age group: 40-64
Pediatric: No
Gender: Male
Genetic Sex: Male
Sex discordant: No
Ethnicity: African American
Predicted genetic ancestry: African (94%), Admixed-American (4%), European (2%)
Dominant genetic ancestry: African

Additional clinical

Diabetes (ontology): MONDO:0005148
T1D stage: Conflicting diabetes evidence
HbA1c-derived diabetes status: Diabetes
Label vs HbA1c discordant: No
Tier 1 complete: Yes
Family history of diabetes: TRUE
Family history relationship: Paternal_greatgrandmother
Living donor: No
Cause of death: Cerebrovascular/Stroke
Donation type: Donation after brain death
Hospital stay (h): 172
Medication: Unknown

Autoantibodies

Summary: GADA+
Any positive: Yes
Tested: Yes
Positive count: 1

GADAPositive

33 unit/ml

IAANegative

0.001 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

-0.001 unit/ml

HLA typing

Status: X/X

Locus	Allele 1	Allele 2	Method
A	2	29	RT-PCR
B	57	78	RT-PCR
Bw4	1	1	RT-PCR
Bw6	1	1	RT-PCR
C	16	18	RT-PCR
DPB1	01:01	02:01	RT-PCR
DQA1	01	04	RT-PCR
DQB1	6	7	RT-PCR
DR	8	13	RT-PCR
DR51	0	0	RT-PCR
DR52	52	—	RT-PCR
DR53	0	0	RT-PCR

Data available

Datasets: Genotyping, HLA_typing, scRNAseq, snATACseq, Function, Imaging, CyTof, Histology, CODEX, imaging_mass_spec
Tissues: unspecified, Islet, Pancreas, Spleen, Lymph

imaging_mass_specAccess dataset

Spleen

histologyAccess dataset

Lymph

histologyAccess dataset

Supplementary

HPAP

Identifiers

PANC-DB:HPAP-108

Pancreas tissue available: Yes
Other tissues: —

Publication identifiers

PMID:31127054, PMID:36206763

Description

Human pancreas donor SAMN25600004 in the HPAP database

External resources

PANC-DB:HPAP-108

URL

https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-108