PKBDO1688VKBU
PKBDO1688VKBU
released
Clinical summary
Diabetes status
Control Without Diabetes
Age (y)
15
Age group
13-17
BMI
23.59
Height (cm)
—
Weight (kg)
—
HbA1c %
5.3
C-Peptide (ng/ml)
5.49
Diabetes duration
—
AAB summary
GADA+, IA2+, ZNT8+
AAB count
3
Demographics
- Age (y)
- 15
- Age group
- 13-17
- Pediatric
- Yes
- Gender
- Male
- Genetic Sex
- Male
- Sex discordant
- No
- Ethnicity
- White
- Predicted genetic ancestry
- European (97%), African (2%), South-Asian (1%)
- Dominant genetic ancestry
- European
Additional clinical
- Diabetes (ontology)
- No ontology term
- T1D stage
- Stage 1: two or more autoantibodies, normal glucose metabolism level
- HbA1c-derived diabetes status
- Normal
- Label vs HbA1c discordant
- No
- Tier 1 complete
- No
- Family history of diabetes
- -
- Living donor
- No
- Cause of death
- Head Trauma
- Donation type
- Donation after circulatory death
- Hospital stay (h)
- 86
Autoantibodies
- Summary
- GADA+, IA2+, ZNT8+
- Any positive
- Yes
- Tested
- Yes
- Positive count
- 3
GADAPositive
848 unit/ml
IAANegative
0.004 unit/ml
IA2Positive
21 unit/ml
ZNT8Positive
0.071 unit/ml
HLA typing
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 03:03 | 32:01 | NGS |
| A | 3 | 32 | RT-PCR |
| B | 27 | 55 | RT-PCR |
| B | 27:02 | 55:01 | NGS |
| Bw4 | 1 | 1 | RT-PCR |
| Bw6 | 1 | 1 | RT-PCR |
| C | 02 | 09 | RT-PCR |
| C | 02:02 | 03:03 | NGS |
| DPA1 | 01:03 | 02:01 | NGS |
| DPB1 | 01:01 | 02:01 | NGS |
| DPB1 | 01:01 | 02:01 | RT-PCR |
| DQA1 | 03 | 05 | RT-PCR |
| DQA1 | 03:01 | 05:01 | NGS |
| DQB1 | 02:01 | 03:02 | NGS |
| DQB1 | 2 | 8 | RT-PCR |
| DR | 4 | 17 | RT-PCR |
| DR51 | 0 | 0 | RT-PCR |
| DR52 | 52 | — | RT-PCR |
| DR53 | 53 | — | RT-PCR |
| DRB1 | 03:01 | 04:01 | NGS |
| DRB3 | 01:01 | — | NGS |
| DRB4 | — | 01:03 | NGS |
| DRB5 | — | — | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, scRNAseq, snATACseq, Function, Imaging, CyTof, Histology, CODEX, scMultiome, TCRseq, BCRseq, CITEseq, Flow_cytometry
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
scRNAseqAccess dataset
snATACseqAccess dataset
FunctionAccess dataset
ImagingAccess dataset
CyTofAccess dataset
Pancreas
histologyAccess dataset
CODEXAccess dataset
Spleen
scMultiomeAccess dataset
TCRseqAccess dataset
BCRseqAccess dataset
CITEseqAccess dataset
Flow_cytometryAccess dataset
histologyAccess dataset
Lymph
Peripheral_blood
Flow_cytometryAccess dataset
Supplementary
HPAP
PANC-DB:HPAP-107
- Pancreas tissue available
- Yes
- Other tissues
Publication data
External resources
PANC-DB:HPAP-107
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
