PKBDO1528QVBI
{
"@context": "/terms/",
"@id": "/human-donors/PKBDO1528QVBI/",
"@type": [
"HumanDonor",
"Donor",
"Item"
],
"aab_count": 0,
"aab_gada": false,
"aab_gada_assay": [],
"aab_gada_value": 0,
"aab_ia2": false,
"aab_ia2_assay": [],
"aab_ia2_value": 0,
"aab_iaa": false,
"aab_iaa_assay": [],
"aab_iaa_value": -0.001,
"aab_positive": false,
"aab_summary": "none positive",
"aab_tested": true,
"aab_znt8": false,
"aab_znt8_assay": [],
"aab_znt8_value": -0.001,
"accession": "PKBDO1528QVBI",
"age": 18,
"age_group": "18-39",
"aliases": [
"klaus-kaestner:HPAP-012"
],
"audit": {
"WARNING": [
{
"category": "missing tier 1 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 1 field `sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier1_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 2 field `glucose_loweing_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier2_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `diabetes_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `other_therapy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `related_donors`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
}
]
},
"award": {
"@id": "/awards/UC4DK112217/",
"name": "UC4DK112217",
"title": "PENN INTEGRATED HUMAN PANCREAS PROCUREMENT AND ANALYSIS PROGRAM"
},
"biosamples": [
"/primary-islet/PKBSM8017CRFP/",
"/primary-cells/PKBSM7441MOTM/",
"/primary-cells/PKBSM2977DNCZ/",
"/primary-cells/PKBSM1986WDDQ/",
"/primary-islet/PKBSM8294NTLC/"
],
"bmi": 29.6,
"c_peptide": 4.1,
"cause_of_death": "Anoxia",
"center_donor_id": "SAMN19776444",
"collections": [
"HPAP"
],
"creation_timestamp": "2024-10-14T22:30:07.726778+00:00",
"data_available": [
{
"dataset": "Genotyping",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "HLA_typing",
"dataset_link": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002465.v1.p1",
"dataset_tissue": "-"
},
{
"dataset": "RNAseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "ATAC-seq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Function",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "Morphology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "CyTof",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "WGBS",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Islet"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "imaging_mass_spec",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Pancreas"
},
{
"dataset": "TCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "BCRseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "CITEseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "Flow_cytometry",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Spleen"
},
{
"dataset": "scMultiome",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
},
{
"dataset": "CITEseq",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
},
{
"dataset": "histology",
"dataset_link": "https://hpap.pmacs.upenn.edu",
"dataset_tissue": "Lymph"
}
],
"data_available_datasets": [
"Genotyping",
"HLA_typing",
"RNAseq",
"ATAC-seq",
"Function",
"Morphology",
"CyTof",
"WGBS",
"Histology",
"imaging_mass_spec",
"TCRseq",
"BCRseq",
"CITEseq",
"Flow_cytometry",
"scMultiome",
"snATACseq",
"scRNAseq"
],
"data_available_keys": [
"Genotyping|unspecified",
"HLA_typing|unspecified",
"RNAseq|Islet",
"ATAC-seq|Islet",
"Function|Islet",
"Morphology|Islet",
"CyTof|Islet",
"WGBS|Islet",
"Histology|Pancreas",
"imaging_mass_spec|Pancreas",
"TCRseq|Spleen",
"BCRseq|Spleen",
"CITEseq|Spleen",
"Flow_cytometry|Spleen",
"Histology|Spleen",
"scMultiome|Lymph",
"snATACseq|Lymph",
"scRNAseq|Lymph",
"CITEseq|Lymph",
"Histology|Lymph"
],
"data_available_tissues": [
"unspecified",
"Islet",
"Pancreas",
"Spleen",
"Lymph"
],
"dbxrefs": [
"PANC-DB:HPAP-012"
],
"derived_diabetes_status": "Normal",
"description": "Human pancreas donor SAMN19776444 in the HPAP database",
"diabetes_status": [],
"diabetes_status_description": "Control Without Diabetes",
"dominant_genetic_ancestry": "European",
"donation_type": "Donation after brain death",
"ethnicities": [
"White"
],
"family_history_of_diabetes": "FALSE",
"gender": "Female",
"genetic_ethnicities": [
{
"ethnicity": "European",
"percentage": 99
},
{
"ethnicity": "East-Asian",
"percentage": 1
}
],
"genetic_sex": "Female",
"hba1c": 4.5,
"hla_typing": [
"A,01:01-24:02,NGS",
"A,1-24,RT-PCR",
"B,15:01-44:02,NGS",
"B,62-44,RT-PCR",
"Bw4,1-.,RT-PCR",
"Bw6,1-.,RT-PCR",
"C,03:04-02:02,NGS",
"C,2-10,RT-PCR",
"DPA1,01:03-.,NGS",
"DPB1,04:01-13:01,NGS",
"DPB1,04:01-13:01,RT-PCR",
"DQA1,03-05,RT-PCR",
"DQA1,03:01-05:05,NGS",
"DQB1,03:02-03:19,NGS",
"DQB1,7-8,RT-PCR",
"DR,4-11,RT-PCR",
"DR51,0-.,RT-PCR",
"DR52,1-.,RT-PCR",
"DR53,1-.,RT-PCR",
"DRB1,11:02-04:01,NGS",
"DRB3,02:02-.,NGS",
"DRB4,.-01:03,NGS",
"DRB5,.-.,NGS"
],
"hospital_stay": 147,
"human_donor_identifiers": [
"PANC-DB:HPAP-012"
],
"lab": {
"@id": "/labs/klaus-kaestner/"
},
"label_hba1c_discordant": false,
"living_donor": false,
"other_tissues_available": [
"/sample-terms/UBERON_0002113/",
"/sample-terms/UBERON_0002107/",
"/sample-terms/UBERON_0001264/"
],
"pancreas_tissue_available": true,
"pediatric": false,
"publication_identifiers": [
"PMID:31127054",
"PMID:36206763"
],
"release_timestamp": "2025-01-10T01:41:06.419188+00:00",
"rrid": "RRID:SAMN19776444",
"schema_version": "23",
"sex_discordant": false,
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitter_comment": "Meta-data was obtained directly from PANC-DB",
"summary": "PKBDO1528QVBI",
"t1d_stage": "No sufficient information to derive",
"taxa": "Homo sapiens",
"tier1_complete": false,
"url": "https://hpap.pmacs.upenn.edu/explore/donor/donor-summary/HPAP-012",
"uuid": "4bf4ded3-0152-4be4-b988-bd29de77936d",
"virtual": false
}
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
