PKBDO1253VULF
PKBDO1253VULF
released
Clinical summary
Diabetes status
Control Without Diabetes
Age (y)
21
Age group
18-39
BMI
25.66
Height (cm)
—
Weight (kg)
—
HbA1c %
5.3
C-Peptide (ng/ml)
11.45
Diabetes duration
—
AAB summary
GADA+
AAB count
1
Demographics
- Age (y)
- 21
- Age group
- 18-39
- Pediatric
- No
- Gender
- Female
- Genetic Sex
- Female
- Sex discordant
- No
- Ethnicity
- White
- Predicted genetic ancestry
- European (99%), African (1%)
- Dominant genetic ancestry
- European
Additional clinical
- Diabetes (ontology)
- No ontology term
- T1D stage
- At-risk: single or transient autoantibody, normal glucose level
- HbA1c-derived diabetes status
- Normal
- Label vs HbA1c discordant
- No
- Tier 1 complete
- No
- Family history of diabetes
- -
- Living donor
- No
- Cause of death
- Head Trauma
- Donation type
- Donation after brain death
- Hospital stay (h)
- 93
Autoantibodies
- Summary
- GADA+
- Any positive
- Yes
- Tested
- Yes
- Positive count
- 1
GADAPositive
531 unit/ml
1
IAANegative
-0.003 unit/ml
IA2Negative
0 unit/ml
ZNT8Negative
-0.001 unit/ml
HLA typing
| Locus | Allele 1 | Allele 2 | Method |
|---|---|---|---|
| A | 01:01 | 02:01 | NGS |
| A | 1 | 2 | RT-PCR |
| B | 08:01 | 44:02 | NGS |
| B | 8 | 44 | RT-PCR |
| Bw4 | 1 | 1 | RT-PCR |
| Bw6 | 1 | 1 | RT-PCR |
| C | 05 | 07 | RT-PCR |
| C | 05:01 | 07:01 | NGS |
| DPA1 | 01:03 | — | NGS |
| DPB1 | 04:01 | 04:02 | NGS |
| DPB1 | 04:01 | 04:02 | RT-PCR |
| DQA1 | 01 | 05 | RT-PCR |
| DQA1 | 01:02 | 05:01 | NGS |
| DQB1 | 02:01 | 06:02 | NGS |
| DQB1 | 2 | 6 | RT-PCR |
| DR | 15 | 17 | RT-PCR |
| DR51 | 5:01 | 0 | RT-PCR |
| DR52 | 3:01 | 0 | RT-PCR |
| DR53 | 0 | 0 | RT-PCR |
| DRB1 | 03:01 | 15:01 | NGS |
| DRB3 | 01:01 | — | NGS |
| DRB5 | — | 01:01 | NGS |
Data available
- Datasets
- Genotyping, HLA_typing, scRNAseq, Function, Imaging, CyTof, Histology, CODEX, TCRseq, BCRseq, CITEseq, Flow_cytometry, scMultiome, snATACseq
- Tissues
- unspecified, Islet, Pancreas, Spleen, Lymph, Peripheral_blood
Genetics
GenotypingAccess dataset
HLA_typingAccess dataset
Islet
Pancreas
histologyAccess dataset
CODEXAccess dataset
Spleen
TCRseqAccess dataset
BCRseqAccess dataset
CITEseqAccess dataset
Flow_cytometryAccess dataset
histologyAccess dataset
Lymph
Peripheral_blood
Flow_cytometryAccess dataset
Supplementary
HPAP
PANC-DB:HPAP-114
- Pancreas tissue available
- Yes
- Other tissues
External resources
PANC-DB:HPAP-114
Attribution
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
