released

PKBDO0188CMQS

released

RRID RRID:SAMN18741942Program Donor ID SAMN18741942

Clinical summary

Diabetes status

Type 1 Diabetes

Age (y)

Age group

18-39

BMI

22.03

Height (cm)

—

Weight (kg)

—

HbA1c %

—

C-Peptide (ng/ml)

0.03

Diabetes duration

AAB summary

IAA+

AAB count

Age (y): 29
Age group: 18-39
Pediatric: No
Gender: Male
Genetic Sex: Male
Sex discordant: No
Ethnicity: White
Predicted genetic ancestry: European (95%), Admixed-American (3%), African (1%), East-Asian (1%)
Dominant genetic ancestry: European

Diabetes (ontology): MONDO:0005147
T1D stage: Stage 3: one or more autoantibodies and diagnostic hyperglycemia or T1D diagnosis
Tier 1 complete: Yes
Family history of diabetes: FALSE
Living donor: No
Cause of death: Head Trauma
Donation type: Donation after circulatory death
Hospital stay (h): 324
Medication: Insulin

GADANegative

0 unit/ml

IAAPositive

0.0161 unit/ml

IA2Negative

0 unit/ml

ZNT8Negative

0 unit/ml

Locus	Allele 1	Allele 2	Method
A	11	24	RT-PCR
A	11:01	24:02	NGS
B	15:01	40:01	NGS
B	62	60	RT-PCR
C	03:03	03:04	NGS
C	10	9	RT-PCR
DPA1	01:03	—	NGS
DPB1	03:01	04:01	NGS
DPB1	03:01	04:01	RT-PCR
DQA1	03	05	RT-PCR
DQA1	03:01	05:05	NGS
DQB1	03:01	03:02	NGS
DQB1	7	8	RT-PCR
DR	4	11	RT-PCR
DR51	0	—	RT-PCR
DR52	1	—	RT-PCR
DR53	1	—	RT-PCR
DRB1	11:01	04:04	NGS
DRB3	02:02	—	NGS
DRB4	—	01:03	NGS
DRB5	—	—	NGS

Datasets: Genotyping, HLA_typing, RNAseq, Function, Imaging, CyTof, Histology, CODEX, imaging_mass_spec, TCRseq, BCRseq, Flow_cytometry
Tissues: unspecified, Islet, Pancreas, Spleen, Lymph