EndoC-bH5 — PKBSM9303JYQG

{
    "@context": "/terms/",
    "@id": "/human-beta-cell-line/PKBSM9303JYQG/",
    "@type": [
        "HumanBetaCellLines",
        "Biosample",
        "Sample",
        "Item"
    ],
    "accession": "PKBSM9303JYQG",
    "age": "unknown",
    "aliases": [
        "pankbase-consortium:EndoC-bH5_treated_IFNgIL1B_GSE224731"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Released human beta cell lines [PKBSM9303JYQG](/human-beta-cell-line/PKBSM9303JYQG/) has in progress subobject sample term [CVCL_C7TU](/sample-terms/CVCL_C7TU/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/human-beta-cell-line/PKBSM9303JYQG/"
            }
        ],
        "WARNING": [
            {
                "category": "incorrect classifications format",
                "detail": "Human beta cell line [PKBSM9303JYQG](/human-beta-cell-line/PKBSM9303JYQG/) has `classifications` ['human beta cell line'] but should be [\"cell line\"]. Human beta cell lines are expected to have classifications as an array.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_classifications_format_check",
                "path": "/human-beta-cell-line/PKBSM9303JYQG/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U24DK138512-DK138515/",
        "component": "data coordination"
    },
    "classifications": [
        "human beta cell line"
    ],
    "coating_condition": "βCoat",
    "creation_timestamp": "2025-10-21T21:46:48.222437+00:00",
    "description": "EndoC-bH5 cells treated with IFNg and IL1B from GSE224731",
    "donors": [
        {
            "@id": "/human-donors/PKBDO8293TLPA/",
            "accession": "PKBDO8293TLPA",
            "age": 0,
            "summary": "PKBDO8293TLPA",
            "taxa": "Homo sapiens"
        }
    ],
    "excision_status": "excised",
    "file_sets": [
        {
            "@id": "/analysis-sets/PKBDS6263SKMX/",
            "accession": "PKBDS6263SKMX",
            "aliases": [
                "pankbase-consortium:EndoC-bH5_treated_IFNgIL1B_GSE224731_AnalysisSet"
            ],
            "lab": {},
            "status": "released"
        },
        {
            "@id": "/measurement-sets/PKBDS2222CRTL/",
            "accession": "PKBDS2222CRTL",
            "aliases": [
                "pankbase-consortium:EndoC-bH5_treated_IFNgIL1B_GSE224731_MeasurementSet"
            ],
            "assay_term": {
                "term_name": "bulk RNA-seq assay"
            },
            "lab": {},
            "status": "released"
        }
    ],
    "growth_medium": "Ulti-β1 culture media",
    "institutional_certificates": [],
    "lab": {
        "@id": "/labs/pankbase-consortium/"
    },
    "multiplexed_in": [],
    "origin_of": [],
    "parts": [],
    "pooled_in": [],
    "publication_identifiers": [
        "PMID:37442376",
        "PMCID:PMC10407753",
        "doi:10.1016/j.molmet.2023.101772"
    ],
    "release_timestamp": "2025-10-27T19:40:52.012932+00:00",
    "sample_name": "EndoC-bH5",
    "sample_terms": [
        {
            "@id": "/sample-terms/CVCL_C7TU/",
            "term_name": "EndoC-bH5"
        }
    ],
    "sorted_fractions": [],
    "sources": [
        {
            "@id": "/sources/r-scharfmann-university-of-paris-france/",
            "title": "R. Scharfmann, University of Paris, France"
        }
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
        "title": "Ying Sun"
    },
    "summary": "EndoC-bH5 cell line, treated with 1000 U/mL Interferon gamma for 24 hours, 2 ng/mL Interleukin-1 beta for 24 hours",
    "treatments": [
        {
            "@id": "/treatments/500a99cc-71f6-4293-9be8-2113f1884b9d/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Treatment of 1000 U/mL Interferon gamma for 24 hours",
            "treatment_type": "protein"
        },
        {
            "@id": "/treatments/e8d3c768-5e02-4cf1-84f0-f495f86f0948/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Treatment of 2 ng/mL Interleukin-1 beta for 24 hours",
            "treatment_type": "protein"
        }
    ],
    "uuid": "b25f8ba5-a309-4fff-a16b-1fbef419d8e7",
    "virtual": false
}