EndoC-βH1 — PKBSM6207TNSY

{
    "@context": "/terms/",
    "@id": "/human-beta-cell-line/PKBSM6207TNSY/",
    "@type": [
        "HumanBetaCellLines",
        "Biosample",
        "Sample",
        "Item"
    ],
    "accession": "PKBSM6207TNSY",
    "age": "unknown",
    "aliases": [
        "pankbase-consortium:EndoC-bh1_treated_T-antigen460SIX2_GSE79469"
    ],
    "audit": {
        "WARNING": [
            {
                "category": "incorrect classifications format",
                "detail": "Human beta cell line [PKBSM6207TNSY](/human-beta-cell-line/PKBSM6207TNSY/) has `classifications` ['human beta cell line'] but should be [\"cell line\"]. Human beta cell lines are expected to have classifications as an array.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_classifications_format_check",
                "path": "/human-beta-cell-line/PKBSM6207TNSY/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U24DK138512-DK138515/",
        "component": "data coordination"
    },
    "classifications": [
        "human beta cell line"
    ],
    "coating_condition": "Matrigel-fibronectin",
    "creation_timestamp": "2025-10-21T18:45:28.850572+00:00",
    "description": "EndoC-bh1 cells treated with T-antigen (460) siRNA and stable expression of SIX2 from GSE79469",
    "donors": [
        {
            "@id": "/human-donors/PKBDO8293TLPA/",
            "accession": "PKBDO8293TLPA",
            "age": 0,
            "summary": "PKBDO8293TLPA",
            "taxa": "Homo sapiens"
        }
    ],
    "file_sets": [
        {
            "@id": "/analysis-sets/PKBDS1784ZYFY/",
            "accession": "PKBDS1784ZYFY",
            "aliases": [
                "pankbase-consortium:EndoC-bh1_treated_T-antigen460SIX2_GSE79469_AnalysisSet"
            ],
            "lab": {
                "title": "Pankbase Consortium, PanKbase"
            },
            "status": "released",
            "summary": "intermediate analysis of RNA-seq data"
        },
        {
            "@id": "/measurement-sets/PKBDS0529GPTE/",
            "accession": "PKBDS0529GPTE",
            "aliases": [
                "pankbase-consortium:EndoC-bh1_treated_T-antigen460SIX2_GSE79469_MeasurementSet"
            ],
            "assay_term": {
                "term_name": "bulk RNA-seq assay"
            },
            "lab": {
                "title": "Pankbase Consortium, PanKbase"
            },
            "status": "released",
            "summary": "bulk RNA-seq assay (RNA-seq)"
        }
    ],
    "growth_medium": "DMEM that contained 5.6 mM glucose, 2% BSA fraction V, 50 μM 2-mercaptoethanol, 10 mM nicotinamide, 5.5 μg/ml transferrin, 6.7 ng/ml selenite, 100 U/ml penicillin, and 100 μg/ml streptomycin",
    "institutional_certificates": [],
    "lab": {
        "@id": "/labs/pankbase-consortium/",
        "title": "Pankbase Consortium, PanKbase"
    },
    "multiplexed_in": [],
    "origin_of": [],
    "parts": [],
    "pooled_in": [],
    "publication_identifiers": [
        "PMID:27133132"
    ],
    "release_timestamp": "2025-10-27T19:40:50.939352+00:00",
    "sample_name": "EndoC-bH1",
    "sample_terms": [
        {
            "@id": "/sample-terms/CVCL_909/",
            "term_name": "EndoC-βH1"
        }
    ],
    "sorted_fractions": [],
    "sources": [
        {
            "@id": "/sources/r-scharfmann-university-of-paris-france/",
            "title": "R. Scharfmann, University of Paris, France"
        }
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
        "title": "Ying Sun"
    },
    "summary": "EndoC-βH1 cell line, depleted of SIX2",
    "taxa": "Homo sapiens",
    "treatments": [
        {
            "@id": "/treatments/b0c9b32d-e8e8-4469-86a0-1661b0878545/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Depletion of SIX2",
            "treatment_type": "protein"
        }
    ],
    "uuid": "d780e326-a8e8-4b67-81e8-9ccb9e4c885e",
    "virtual": false
}