EndoC-βH1 — PKBSM2973NJDC

{
    "@context": "/terms/",
    "@id": "/human-beta-cell-line/PKBSM2973NJDC/",
    "@type": [
        "HumanBetaCellLines",
        "Biosample",
        "Sample",
        "Item"
    ],
    "accession": "PKBSM2973NJDC",
    "age": "unknown",
    "aliases": [
        "pankbase-consortium:EndoC-bH1_treated_NLRC5IFNa8hr_GSE202852"
    ],
    "audit": {
        "WARNING": [
            {
                "category": "incorrect classifications format",
                "detail": "Human beta cell line [PKBSM2973NJDC](/human-beta-cell-line/PKBSM2973NJDC/) has `classifications` ['human beta cell line'] but should be [\"cell line\"]. Human beta cell lines are expected to have classifications as an array.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_classifications_format_check",
                "path": "/human-beta-cell-line/PKBSM2973NJDC/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U24DK138512-DK138515/",
        "component": "data coordination"
    },
    "classifications": [
        "human beta cell line"
    ],
    "coating_condition": "Matrigel-fibronectin",
    "creation_timestamp": "2025-10-21T18:44:31.662383+00:00",
    "description": "EndoC-bH1 cells treated with NLRC5 siRNA and IFNa for 8hr from GSE202852",
    "donors": [
        {
            "@id": "/human-donors/PKBDO8293TLPA/",
            "accession": "PKBDO8293TLPA",
            "age": 0,
            "summary": "PKBDO8293TLPA",
            "taxa": "Homo sapiens"
        }
    ],
    "file_sets": [
        {
            "@id": "/analysis-sets/PKBDS6594ODIR/",
            "accession": "PKBDS6594ODIR",
            "aliases": [
                "pankbase-consortium:EndoC-bH1_treated_NLRC5IFNa8hr_GSE202852_AnalysisSet"
            ],
            "lab": {
                "title": "Pankbase Consortium, PanKbase"
            },
            "status": "released",
            "summary": "intermediate analysis of RNA-seq data"
        },
        {
            "@id": "/measurement-sets/PKBDS2410GQJF/",
            "accession": "PKBDS2410GQJF",
            "aliases": [
                "pankbase-consortium:EndoC-bH1_treated_NLRC5IFNa8hr_GSE202852_MeasurementSet"
            ],
            "assay_term": {
                "term_name": "bulk RNA-seq assay"
            },
            "lab": {
                "title": "Pankbase Consortium, PanKbase"
            },
            "status": "released",
            "summary": "bulk RNA-seq assay (RNA-seq)"
        }
    ],
    "growth_medium": "Dulbecco’s modified Eagle medium with 5.6 mM glucose, 2% fatty acid–free BSA fraction V, 50 μM 2-mercaptoethanol, 10 mM nicotinamide, transferrin, selenite (6.7 ng/ml), and penicillin (100 U/ml) + streptomycin (100 μg/ml)",
    "institutional_certificates": [],
    "lab": {
        "@id": "/labs/pankbase-consortium/",
        "title": "Pankbase Consortium, PanKbase"
    },
    "multiplexed_in": [],
    "nucleic_acid_delivery": "Lipofectamine RNAiMAX",
    "origin_of": [],
    "parts": [],
    "pooled_in": [],
    "publication_identifiers": [
        "PMID:36103539"
    ],
    "release_timestamp": "2025-10-27T19:40:48.839003+00:00",
    "sample_name": "EndoC-bH1",
    "sample_terms": [
        {
            "@id": "/sample-terms/CVCL_909/",
            "term_name": "EndoC-βH1"
        }
    ],
    "sorted_fractions": [],
    "sources": [
        {
            "@id": "/sources/r-scharfmann-university-of-paris-france/",
            "title": "R. Scharfmann, University of Paris, France"
        }
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
        "title": "Ying Sun"
    },
    "summary": "EndoC-βH1 cell line, depleted of NLRC5 for 8 hours, treated with 2000 U/mL Interferon alpha for 8 hours",
    "taxa": "Homo sapiens",
    "treatments": [
        {
            "@id": "/treatments/62d13850-0bae-431b-83d0-692944432149/",
            "purpose": "perturbation",
            "status": "released",
            "summary": "Depletion of NLRC5 for 8 hours",
            "treatment_type": "protein"
        },
        {
            "@id": "/treatments/21937b6f-030e-445a-b017-66bd25a7fa65/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Treatment of 2000 U/mL Interferon alpha for 8 hours",
            "treatment_type": "protein"
        }
    ],
    "uuid": "f9fb8a9c-9d58-4d82-b655-e665dc48a14e",
    "virtual": false
}