EndoC-βH1 — PKBSM2497EGUQ

{
    "@context": "/terms/",
    "@id": "/human-beta-cell-line/PKBSM2497EGUQ/",
    "@type": [
        "HumanBetaCellLines",
        "Biosample",
        "Sample",
        "Item"
    ],
    "accession": "PKBSM2497EGUQ",
    "age": "unknown",
    "aliases": [
        "pankbase-consortium:EndoC-bH1_treated_SPOCK2OverExpVector_GSE190361"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Released human beta cell lines [PKBSM2497EGUQ](/human-beta-cell-line/PKBSM2497EGUQ/) has in progress subobject source [univercell-biosolutions](/sources/univercell-biosolutions/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/human-beta-cell-line/PKBSM2497EGUQ/"
            }
        ],
        "WARNING": [
            {
                "category": "incorrect classifications format",
                "detail": "Human beta cell line [PKBSM2497EGUQ](/human-beta-cell-line/PKBSM2497EGUQ/) has `classifications` ['human beta cell line'] but should be [\"cell line\"]. Human beta cell lines are expected to have classifications as an array.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_classifications_format_check",
                "path": "/human-beta-cell-line/PKBSM2497EGUQ/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U24DK138512-DK138515/",
        "component": "data coordination"
    },
    "classifications": [
        "human beta cell line"
    ],
    "coating_condition": "Geltrex, fibronectin",
    "creation_timestamp": "2025-10-21T18:44:50.522975+00:00",
    "description": "EndoC-bH1 cells treated with SPOCK2 overexpression vector from GSE190361",
    "donors": [
        {
            "@id": "/human-donors/PKBDO8293TLPA/",
            "accession": "PKBDO8293TLPA",
            "age": 0,
            "summary": "PKBDO8293TLPA",
            "taxa": "Homo sapiens"
        }
    ],
    "file_sets": [
        {
            "@id": "/analysis-sets/PKBDS8526PCAT/",
            "accession": "PKBDS8526PCAT",
            "aliases": [
                "pankbase-consortium:EndoC-bH1_treated_SPOCK2OverExpVector_GSE190361_AnalysisSet"
            ],
            "lab": {
                "title": "Pankbase Consortium, PanKbase"
            },
            "status": "released",
            "summary": "intermediate analysis of RNA-seq data"
        },
        {
            "@id": "/measurement-sets/PKBDS2353XDFL/",
            "accession": "PKBDS2353XDFL",
            "aliases": [
                "pankbase-consortium:EndoC-bH1_treated_SPOCK2OverExpVector_GSE190361_MeasurementSet"
            ],
            "assay_term": {
                "term_name": "bulk RNA-seq assay"
            },
            "lab": {
                "title": "Pankbase Consortium, PanKbase"
            },
            "status": "released",
            "summary": "bulk RNA-seq assay (RNA-seq)"
        }
    ],
    "growth_medium": "Dulbecco’s modified Eagle’s medium containing 1g/L glucose (DMEM) supplemented with 2% BSA fraction V fatty acid free, 50 μM 2-mercaptoethanol, 10 mM nicotinamide, 5.5 μg/ml transferrin, 6.7 ng/ml selenite, 100 U/ml penicillin, and 100 μg/ml streptomycin",
    "institutional_certificates": [],
    "lab": {
        "@id": "/labs/pankbase-consortium/",
        "title": "Pankbase Consortium, PanKbase"
    },
    "multiplexed_in": [],
    "nucleic_acid_delivery": "Lipofectamine 3000",
    "origin_of": [],
    "parts": [],
    "pooled_in": [],
    "publication_identifiers": [
        "PMID:39741186"
    ],
    "release_timestamp": "2025-10-27T19:40:49.225655+00:00",
    "sample_name": "EndoC-bH1",
    "sample_terms": [
        {
            "@id": "/sample-terms/CVCL_909/",
            "term_name": "EndoC-βH1"
        }
    ],
    "sorted_fractions": [],
    "sources": [
        {
            "@id": "/sources/univercell-biosolutions/",
            "title": "Univercell Biosolutions"
        }
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
        "title": "Ying Sun"
    },
    "summary": "EndoC-βH1 cell line, depleted of SPOCK2",
    "taxa": "Homo sapiens",
    "treatments": [
        {
            "@id": "/treatments/a5a0dc18-c05d-4b3f-bd41-561ab532f995/",
            "purpose": "stimulation",
            "status": "released",
            "summary": "Depletion of SPOCK2",
            "treatment_type": "protein"
        }
    ],
    "uuid": "c4cd3d8b-e99a-497e-9c9b-a20c0add0c1b",
    "virtual": false
}