{
"@context": "/terms/",
"@id": "/analysis-sets/PKBDS6993KIMS/",
"@type": [
"AnalysisSet",
"FileSet",
"Item"
],
"accession": "PKBDS6993KIMS",
"aliases": [
"klaus-kaestner:pancreaticAlphaCell_AnalysisSet_RNAseq_HPAP-083"
],
"assay_titles": [
"RNA-seq"
],
"audit": {
"ERROR": [
{
"category": "inconsistent parent sample",
"detail": "Primary cell [PKBSM8567TLYO](/primary-cells/PKBSM8567TLYO/) has metadata properties (`islet_function_available`, `rrid`, `islet_histology`, `pancreas_weight`, `sample_terms`, `islet_yield`, `pre_shipment_culture_time`, `isolation_center`, `lower_bound_age`, `hand_picked`, `cold_ischaemia_time`, `purity`, `age_units`, `islet_morphology`, `upper_bound_age`, `preservation_method`, `prep_viability`, `organ_source`) inconsistent with its associated parent sample [PKBSM6804RYNG](/primary-islet/PKBSM6804RYNG/). Samples that are sorted from or part of a parent sample are expected to share most of the parent's metadata properties.",
"level": 60,
"level_name": "ERROR",
"name": "audit_sample_sorted_from_parent_child_check",
"path": "/primary-cells/PKBSM8567TLYO/"
},
{
"category": "unexpected input file set",
"detail": "Analysis set [PKBDS6993KIMS](/analysis-sets/PKBDS6993KIMS/) links to file set(s): [PKBDS9911KOYP](/measurement-sets/PKBDS9911KOYP/) in `input_file_sets` that are not represented in the `derived_from` of the file sets of the files in this analysis. The analysis set input files are expected to belong to the input file sets.",
"level": 60,
"level_name": "ERROR",
"name": "audit_input_file_sets_derived_from",
"path": "/analysis-sets/PKBDS6993KIMS/"
}
],
"WARNING": [
{
"category": "missing age",
"detail": "Primary cell [PKBSM8567TLYO](/primary-cells/PKBSM8567TLYO/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
"level": 40,
"level_name": "WARNING",
"name": "audit_biosample_age",
"path": "/primary-cells/PKBSM8567TLYO/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 2 field `diabetes_status_hba1c`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/human-donors/PKBDO1723DEAS/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1723DEAS/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1723DEAS/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `biological_sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1723DEAS/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1723DEAS](/human-donors/PKBDO1723DEAS/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1723DEAS/"
},
{
"category": "missing files",
"detail": "Analysis set [PKBDS6993KIMS](/analysis-sets/PKBDS6993KIMS/) has no `files`. File sets are expected to have files.",
"level": 40,
"level_name": "WARNING",
"name": "audit_no_files",
"path": "/analysis-sets/PKBDS6993KIMS/"
}
]
},
"award": {
"@id": "/awards/U01DK123594/",
"contact_pi": {
"@id": "/users/e1c8c91f-3952-45a9-9f56-442627f60c13/",
"title": "Klaus Kaestner"
},
"title": "THE HUMAN PANCREAS ANALYSIS PROGRAM FOR TYPE 2 DIABETES"
},
"collections": [
"HPAP"
],
"control_for": [],
"creation_timestamp": "2024-12-05T18:10:10.768048+00:00",
"description": "Analysis set of RNA-seq for pancreatic alpha cell of islet biosample from human donor SAMN19842612 in the HPAP database HPAP-083",
"donors": [
{
"@id": "/human-donors/PKBDO1723DEAS/",
"accession": "PKBDO1723DEAS",
"aliases": [
"klaus-kaestner:HPAP-083"
],
"sex": "male",
"status": "released",
"taxa": "Homo sapiens"
}
],
"file_set_type": "intermediate analysis",
"files": [],
"input_file_set_for": [],
"input_file_sets": [
{
"@id": "/measurement-sets/PKBDS9911KOYP/",
"accession": "PKBDS9911KOYP",
"aliases": [
"klaus-kaestner:pancreaticAlphaCell_MeasurementSet_RNAseq_HPAP-083"
],
"file_set_type": "experimental data"
}
],
"lab": {
"@id": "/labs/klaus-kaestner/",
"title": "Klaus Kaestner, UPenn"
},
"publication_identifiers": [
"PMID:31127054",
"PMCID:PMC6609987",
"doi:10.2337/db19-0058",
"PMID:36206763",
"PMCID:PMC9742126",
"doi:10.1016/j.cmet.2022.09.013"
],
"release_timestamp": "2025-01-10T10:14:08.839693+00:00",
"samples": [
{
"@id": "/primary-cells/PKBSM8567TLYO/",
"@type": [
"PrimaryCell",
"Biosample",
"Sample",
"Item"
],
"accession": "PKBSM8567TLYO",
"aliases": [
"klaus-kaestner:pancreaticAlphaCell_HPAP-083"
],
"sample_terms": [
{
"@id": "/sample-terms/CL_0000171/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"kyle-gaulton:sample_pancreaticAcell"
],
"status": "released",
"summary": "pancreatic A cell",
"term_name": "pancreatic A cell"
}
],
"status": "released",
"summary": "pancreatic A cell, male, Homo sapiens",
"taxa": "Homo sapiens"
}
],
"schema_version": "7",
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitter_comment": "HPAP-083",
"summary": "intermediate analysis of RNA-seq data",
"uuid": "ddb3f262-9003-45c0-a3d6-e27c63fbbeb6"
}