PKBDS6685OCTO

released
{
    "@context": "/terms/",
    "@id": "/analysis-sets/PKBDS6685OCTO/",
    "@type": [
        "AnalysisSet",
        "FileSet",
        "Item"
    ],
    "accession": "PKBDS6685OCTO",
    "aliases": [
        "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet"
    ],
    "assay_titles": [
        "RNA-seq"
    ],
    "audit": {
        "ERROR": [
            {
                "category": "unexpected input file set",
                "detail": "Analysis set [PKBDS6685OCTO](/analysis-sets/PKBDS6685OCTO/) links to file set(s): [PKBDS7487USBN](/measurement-sets/PKBDS7487USBN/) in `input_file_sets` that are not represented in the `derived_from` of the file sets of the files in this analysis. The analysis set input files are expected to belong to the input file sets.",
                "level": 60,
                "level_name": "ERROR",
                "name": "audit_input_file_sets_derived_from",
                "path": "/analysis-sets/PKBDS6685OCTO/"
            }
        ],
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Released human beta cell lines [PKBSM6845SNYE](/human-beta-cell-line/PKBSM6845SNYE/) has in progress subobject source [endocell](/sources/endocell/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/human-beta-cell-line/PKBSM6845SNYE/"
            },
            {
                "category": "mismatched status",
                "detail": "Released human beta cell lines [PKBSM6845SNYE](/human-beta-cell-line/PKBSM6845SNYE/) has in progress subobject sample term [CVCL_IS71](/sample-terms/CVCL_IS71/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/human-beta-cell-line/PKBSM6845SNYE/"
            }
        ],
        "WARNING": [
            {
                "category": "missing derived from",
                "detail": "Analysis set [PKBDS6685OCTO](/analysis-sets/PKBDS6685OCTO/) links to file(s) [PKBFI5353TTLY](/alignment-files/PKBFI5353TTLY/), [PKBFI4872WSPN](/alignment-files/PKBFI4872WSPN/), [PKBFI8593OULL](/alignment-files/PKBFI8593OULL/), [PKBFI5238YHLU](/alignment-files/PKBFI5238YHLU/), [PKBFI9725VTBP](/alignment-files/PKBFI9725VTBP/), [PKBFI4859OZMR](/alignment-files/PKBFI4859OZMR/), [PKBFI9609JMFZ](/tabular-files/PKBFI9609JMFZ/), [PKBFI5782HTEE](/tabular-files/PKBFI5782HTEE/), [PKBFI3104RPJS](/tabular-files/PKBFI3104RPJS/) that have no `derived_from`. Files in an analysis set are expected to be derived from other files.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_input_file_sets_derived_from",
                "path": "/analysis-sets/PKBDS6685OCTO/"
            },
            {
                "category": "missing tier 1 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 1 field `sex`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier1_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 1 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 1 field `bmi`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier1_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 1 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 1 field `diabetes_status_description`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier1_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 2 field `rrid`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier2_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 2 field `ethnicities`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier2_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 2 field `hba1c`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier2_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 2 field `glucose_loweing_theraphy`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier2_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 2 field `hospital_stay`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier2_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 2 field `donation_type`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier2_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 2 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 2 field `cause_of_death`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier2_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `dbxrefs`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `phenotypic_features`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `family_history_of_diabetes`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `genetic_ethnicities`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `genetic_sex`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `diabetes_duration`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `c_peptide`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_gada`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_gada_assay`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_gada_value`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_ia2`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_ia2_assay`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_ia2_value`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_iaa`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_iaa_assay`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_iaa_value`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_znt8`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_znt8_assay`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `aab_znt8_value`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `hla_typing`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `other_theraphy`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `publication_identifiers`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `collections`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `pancreas_tissue_available`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `documents`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `url`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `derived_diabetes_status`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `data_available`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "missing tier 3 field",
                "detail": "Human donor [PKBDO8293TLPA](/human-donors/PKBDO8293TLPA/) is missing tier 3 field `related_donors`.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_tier3_fields",
                "path": "/human-donors/PKBDO8293TLPA/"
            },
            {
                "category": "incorrect classifications format",
                "detail": "Human beta cell line [PKBSM6845SNYE](/human-beta-cell-line/PKBSM6845SNYE/) has `classifications` ['human beta cell line'] but should be [\"cell line\"]. Human beta cell lines are expected to have classifications as an array.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_classifications_format_check",
                "path": "/human-beta-cell-line/PKBSM6845SNYE/"
            }
        ]
    },
    "award": {
        "@id": "/awards/U24DK138512-DK138515/",
        "component": "data coordination",
        "title": "A Data and Administrative Coordinating Center for the PanKbase Consortium U24DK138512-DK138515"
    },
    "control_for": [],
    "creation_timestamp": "2025-10-30T18:44:17.305266+00:00",
    "description": "Analysis set of EndoC-bH2 cells treated with extreme hyperglycemia from GSE212749",
    "donors": [
        {
            "@id": "/human-donors/PKBDO8293TLPA/",
            "accession": "PKBDO8293TLPA",
            "aliases": [
                "pankbase-consortium:EndoC_donor"
            ],
            "status": "released",
            "taxa": "Homo sapiens"
        }
    ],
    "file_set_type": "intermediate analysis",
    "files": [
        {
            "@id": "/alignment-files/PKBFI7578IYSQ/",
            "accession": "PKBFI7578IYSQ",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685512.Aligned.sortedByCoord.out.md.bam"
            ],
            "content_type": "alignments",
            "creation_timestamp": "2026-01-06T20:47:41.381911+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI7578IYSQ/@@download/PKBFI7578IYSQ.bam"
        },
        {
            "@id": "/alignment-files/PKBFI5353TTLY/",
            "accession": "PKBFI5353TTLY",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685513.Aligned.toTranscriptome.out.bam"
            ],
            "content_type": "transcriptome alignments",
            "creation_timestamp": "2026-01-06T20:47:43.423867+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI5353TTLY/@@download/PKBFI5353TTLY.bam"
        },
        {
            "@id": "/alignment-files/PKBFI5300CSPQ/",
            "accession": "PKBFI5300CSPQ",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685513.Aligned.sortedByCoord.out.md.bam"
            ],
            "content_type": "alignments",
            "creation_timestamp": "2026-01-06T20:47:44.462273+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI5300CSPQ/@@download/PKBFI5300CSPQ.bam"
        },
        {
            "@id": "/alignment-files/PKBFI4872WSPN/",
            "accession": "PKBFI4872WSPN",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685512.Aligned.sortedByCoord.out.bam"
            ],
            "content_type": "alignments",
            "creation_timestamp": "2026-01-06T20:47:39.095274+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI4872WSPN/@@download/PKBFI4872WSPN.bam"
        },
        {
            "@id": "/alignment-files/PKBFI8593OULL/",
            "accession": "PKBFI8593OULL",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685512.Aligned.toTranscriptome.out.bam"
            ],
            "content_type": "transcriptome alignments",
            "creation_timestamp": "2026-01-06T20:47:40.282219+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI8593OULL/@@download/PKBFI8593OULL.bam"
        },
        {
            "@id": "/alignment-files/PKBFI5238YHLU/",
            "accession": "PKBFI5238YHLU",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685513.Aligned.sortedByCoord.out.bam"
            ],
            "content_type": "alignments",
            "creation_timestamp": "2026-01-06T20:47:42.475176+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI5238YHLU/@@download/PKBFI5238YHLU.bam"
        },
        {
            "@id": "/alignment-files/PKBFI9725VTBP/",
            "accession": "PKBFI9725VTBP",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685511.Aligned.sortedByCoord.out.bam"
            ],
            "content_type": "alignments",
            "creation_timestamp": "2026-01-06T20:47:35.559730+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI9725VTBP/@@download/PKBFI9725VTBP.bam"
        },
        {
            "@id": "/alignment-files/PKBFI4859OZMR/",
            "accession": "PKBFI4859OZMR",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685511.Aligned.toTranscriptome.out.bam"
            ],
            "content_type": "transcriptome alignments",
            "creation_timestamp": "2026-01-06T20:47:36.646024+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI4859OZMR/@@download/PKBFI4859OZMR.bam"
        },
        {
            "@id": "/alignment-files/PKBFI3243OKFH/",
            "accession": "PKBFI3243OKFH",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685511.Aligned.sortedByCoord.out.md.bam"
            ],
            "content_type": "alignments",
            "creation_timestamp": "2026-01-06T20:47:37.766619+00:00",
            "file_format": "bam",
            "href": "/alignment-files/PKBFI3243OKFH/@@download/PKBFI3243OKFH.bam"
        },
        {
            "@id": "/tabular-files/PKBFI1785MLZZ/",
            "accession": "PKBFI1785MLZZ",
            "aliases": [
                "pankbase-consortium:EndoC-bH2_treated_extremeHyperglycemia_GSE212749_AnalysisSet.SAMN30685511.Aligned.sortedByCoord.out.md.marked_dup_metrics.txt"
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