{
"@context": "/terms/",
"@id": "/analysis-sets/PKBDS2287WOIF/",
"@type": [
"AnalysisSet",
"FileSet",
"Item"
],
"accession": "PKBDS2287WOIF",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment"
],
"assay_titles": [
"scRNA-seq"
],
"audit": {
"ERROR": [
{
"category": "unexpected input file set",
"detail": "Analysis set [PKBDS2287WOIF](/analysis-sets/PKBDS2287WOIF/) links to file set(s): [PKBDS4915KOIO](/measurement-sets/PKBDS4915KOIO/) in `input_file_sets` that are not represented in the `derived_from` of the file sets of the files in this analysis. The analysis set input files are expected to belong to the input file sets.",
"level": 60,
"level_name": "ERROR",
"name": "audit_input_file_sets_derived_from",
"path": "/analysis-sets/PKBDS2287WOIF/"
}
],
"INTERNAL_ACTION": [
{
"category": "validation error",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) has schema error Additional properties are not allowed ('glucose_loweing_theraphy' was unexpected).",
"level": 30,
"level_name": "INTERNAL_ACTION",
"name": "audit_item_schema",
"path": "/human-donors/PKBDO5476TMJJ/"
}
],
"WARNING": [
{
"category": "missing derived from",
"detail": "Analysis set [PKBDS2287WOIF](/analysis-sets/PKBDS2287WOIF/) links to file(s) [PKBFI1060GIAO](/alignment-files/PKBFI1060GIAO/), [PKBFI8973MFRF](/tabular-files/PKBFI8973MFRF/), [PKBFI3793UOYX](/tabular-files/PKBFI3793UOYX/), [PKBFI6027ZYVD](/matrix-files/PKBFI6027ZYVD/), [PKBFI5648VTVM](/tabular-files/PKBFI5648VTVM/), [PKBFI7249BNRW](/matrix-files/PKBFI7249BNRW/), [PKBFI2698TZJH](/matrix-files/PKBFI2698TZJH/), [PKBFI2426WGUB](/matrix-files/PKBFI2426WGUB/), [PKBFI3019QRKU](/matrix-files/PKBFI3019QRKU/), [PKBFI4528UBNU](/matrix-files/PKBFI4528UBNU/), [PKBFI9979JDPN](/matrix-files/PKBFI9979JDPN/), [PKBFI5008DXFN](/matrix-files/PKBFI5008DXFN/) that have no `derived_from`. Files in an analysis set are expected to be derived from other files.",
"level": 40,
"level_name": "WARNING",
"name": "audit_input_file_sets_derived_from",
"path": "/analysis-sets/PKBDS2287WOIF/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `aab_gada_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `aab_ia2_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `aab_iaa_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `aab_znt8_assay`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `other_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO5476TMJJ](/human-donors/PKBDO5476TMJJ/) is missing tier 3 field `related_donors`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO5476TMJJ/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM2200JUWJ](/primary-islet/PKBSM2200JUWJ/) is missing tier 2 field `warm_ischaemia_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM2200JUWJ/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM2200JUWJ](/primary-islet/PKBSM2200JUWJ/) is missing tier 2 field `pre_shipment_culture_time`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM2200JUWJ/"
}
]
},
"award": {
"@id": "/awards/U01DK123594/",
"contact_pi": {
"@id": "/users/e1c8c91f-3952-45a9-9f56-442627f60c13/",
"title": "Klaus Kaestner"
},
"title": "THE HUMAN PANCREAS ANALYSIS PROGRAM FOR TYPE 2 DIABETES"
},
"collections": [
"HPAP"
],
"control_for": [],
"creation_timestamp": "2025-05-08T23:19:22.514558+00:00",
"description": "Analysis set of scRNA-seq for islet biosample of human donor HPAP-096 from HPAP with no_treatment (HPAP-096)",
"donors": [
{
"@id": "/human-donors/PKBDO5476TMJJ/",
"accession": "PKBDO5476TMJJ",
"aliases": [
"klaus-kaestner:HPAP-096"
],
"sex": "female",
"status": "released",
"taxa": "Homo sapiens"
}
],
"file_set_type": "intermediate analysis",
"files": [
{
"@id": "/alignment-files/PKBFI1060GIAO/",
"accession": "PKBFI1060GIAO",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Alignment_.Aligned.sortedByCoord.out.bam"
],
"content_type": "alignments",
"creation_timestamp": "2025-05-15T23:57:31.120266+00:00",
"file_format": "bam",
"href": "/alignment-files/PKBFI1060GIAO/@@download/PKBFI1060GIAO.bam"
},
{
"@id": "/tabular-files/PKBFI8973MFRF/",
"accession": "PKBFI8973MFRF",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_.Log.final.out"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-15T23:34:13.745748+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI8973MFRF/@@download/PKBFI8973MFRF.txt.gz"
},
{
"@id": "/tabular-files/PKBFI3793UOYX/",
"accession": "PKBFI3793UOYX",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_.Log.out"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-15T23:39:48.860084+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI3793UOYX/@@download/PKBFI3793UOYX.txt.gz"
},
{
"@id": "/matrix-files/PKBFI6027ZYVD/",
"accession": "PKBFI6027ZYVD",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Matrix_matrix.mtx"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T16:45:44.459852+00:00",
"file_format": "mtx",
"href": "/matrix-files/PKBFI6027ZYVD/@@download/PKBFI6027ZYVD.mtx"
},
{
"@id": "/tabular-files/PKBFI5648VTVM/",
"accession": "PKBFI5648VTVM",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_.Log.progress.out"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-15T23:45:47.479082+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI5648VTVM/@@download/PKBFI5648VTVM.txt.gz"
},
{
"@id": "/alignment-files/PKBFI5593NZCC/",
"accession": "PKBFI5593NZCC",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Alignment_.before-dedup.bam"
],
"content_type": "alignments",
"creation_timestamp": "2025-05-16T16:59:38.304419+00:00",
"file_format": "bam",
"href": "/alignment-files/PKBFI5593NZCC/@@download/PKBFI5593NZCC.bam"
},
{
"@id": "/matrix-files/PKBFI7249BNRW/",
"accession": "PKBFI7249BNRW",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Matrix_cellbender_FPR_0.05_filtered.h5"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T19:19:08.427974+00:00",
"file_format": "h5ad",
"href": "/matrix-files/PKBFI7249BNRW/@@download/PKBFI7249BNRW.h5ad"
},
{
"@id": "/tabular-files/PKBFI3285YAFV/",
"accession": "PKBFI3285YAFV",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_.qc.txt"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T17:23:05.636044+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI3285YAFV/@@download/PKBFI3285YAFV.txt.gz"
},
{
"@id": "/tabular-files/PKBFI8093QGKB/",
"accession": "PKBFI8093QGKB",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_knee.txt"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T17:35:17.551801+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI8093QGKB/@@download/PKBFI8093QGKB.txt.gz"
},
{
"@id": "/matrix-files/PKBFI2698TZJH/",
"accession": "PKBFI2698TZJH",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Matrix_cellbender_FPR_0.05.h5"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T19:10:50.221988+00:00",
"file_format": "h5ad",
"href": "/matrix-files/PKBFI2698TZJH/@@download/PKBFI2698TZJH.h5ad"
},
{
"@id": "/tabular-files/PKBFI5655XCDV/",
"accession": "PKBFI5655XCDV",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_pass.txt"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T17:41:42.657513+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI5655XCDV/@@download/PKBFI5655XCDV.txt.gz"
},
{
"@id": "/tabular-files/PKBFI3761KIZX/",
"accession": "PKBFI3761KIZX",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_cellbender_cell_barcodes.csv"
],
"content_type": "sequence barcodes",
"creation_timestamp": "2025-05-16T17:52:21.375172+00:00",
"file_format": "csv",
"href": "/tabular-files/PKBFI3761KIZX/@@download/PKBFI3761KIZX.csv.gz"
},
{
"@id": "/tabular-files/PKBFI2861LBXK/",
"accession": "PKBFI2861LBXK",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_cellbender_FPR_0.05_metrics.csv"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T18:47:10.826339+00:00",
"file_format": "csv",
"href": "/tabular-files/PKBFI2861LBXK/@@download/PKBFI2861LBXK.csv.gz"
},
{
"@id": "/tabular-files/PKBFI4827ZAHZ/",
"accession": "PKBFI4827ZAHZ",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_cellbender_FPR_0.05_report.html"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T19:45:53.266251+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI4827ZAHZ/@@download/PKBFI4827ZAHZ.txt.gz"
},
{
"@id": "/tabular-files/PKBFI5091CAUB/",
"accession": "PKBFI5091CAUB",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_cellbender_FPR_0.15_report.html"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T21:28:44.640846+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI5091CAUB/@@download/PKBFI5091CAUB.txt.gz"
},
{
"@id": "/matrix-files/PKBFI2426WGUB/",
"accession": "PKBFI2426WGUB",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Matrix_cellbender_FPR_0.1.h5"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T20:02:03.089617+00:00",
"file_format": "h5ad",
"href": "/matrix-files/PKBFI2426WGUB/@@download/PKBFI2426WGUB.h5ad"
},
{
"@id": "/matrix-files/PKBFI3019QRKU/",
"accession": "PKBFI3019QRKU",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Matrix_cellbender_FPR_0.1_filtered.h5"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T20:06:36.493185+00:00",
"file_format": "h5ad",
"href": "/matrix-files/PKBFI3019QRKU/@@download/PKBFI3019QRKU.h5ad"
},
{
"@id": "/tabular-files/PKBFI2282EDEX/",
"accession": "PKBFI2282EDEX",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_cellbender_FPR_0.1_metrics.csv"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T20:30:26.496790+00:00",
"file_format": "csv",
"href": "/tabular-files/PKBFI2282EDEX/@@download/PKBFI2282EDEX.csv.gz"
},
{
"@id": "/tabular-files/PKBFI2970UIQV/",
"accession": "PKBFI2970UIQV",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_cellbender_FPR_0.1_report.html"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T20:39:56.921434+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI2970UIQV/@@download/PKBFI2970UIQV.txt.gz"
},
{
"@id": "/matrix-files/PKBFI4528UBNU/",
"accession": "PKBFI4528UBNU",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Matrix_cellbender_FPR_0.15.h5"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T21:03:00.151871+00:00",
"file_format": "h5ad",
"href": "/matrix-files/PKBFI4528UBNU/@@download/PKBFI4528UBNU.h5ad"
},
{
"@id": "/matrix-files/PKBFI9979JDPN/",
"accession": "PKBFI9979JDPN",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Matrix_cellbender_FPR_0.15_filtered.h5"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T21:08:01.294787+00:00",
"file_format": "h5ad",
"href": "/matrix-files/PKBFI9979JDPN/@@download/PKBFI9979JDPN.h5ad"
},
{
"@id": "/tabular-files/PKBFI0518AIJI/",
"accession": "PKBFI0518AIJI",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_cellbender_FPR_0.15_metrics.csv"
],
"content_type": "QC metrics",
"creation_timestamp": "2025-05-16T21:23:03.259460+00:00",
"file_format": "csv",
"href": "/tabular-files/PKBFI0518AIJI/@@download/PKBFI0518AIJI.csv.gz"
},
{
"@id": "/tabular-files/PKBFI8546AAPW/",
"accession": "PKBFI8546AAPW",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_doubletfinder_assignments.txt"
],
"content_type": "barcode to element mapping",
"creation_timestamp": "2025-05-16T21:34:15.581970+00:00",
"file_format": "txt",
"href": "/tabular-files/PKBFI8546AAPW/@@download/PKBFI8546AAPW.txt.gz"
},
{
"@id": "/tabular-files/PKBFI2432GUOY/",
"accession": "PKBFI2432GUOY",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_Tabular_barcodes.tsv"
],
"content_type": "barcode to element mapping",
"creation_timestamp": "2025-05-16T21:40:13.078482+00:00",
"file_format": "tsv",
"href": "/tabular-files/PKBFI2432GUOY/@@download/PKBFI2432GUOY.tsv.gz"
},
{
"@id": "/matrix-files/PKBFI5008DXFN/",
"accession": "PKBFI5008DXFN",
"aliases": [
"klaus-kaestner:HPAP_scRNAseq_HPAP-096_no_treatment_doubletFiinderMatrix_matrix.mtx"
],
"content_type": "sparse gene count matrix",
"creation_timestamp": "2025-05-16T22:25:18.028618+00:00",
"file_format": "mtx",
"href": "/matrix-files/PKBFI5008DXFN/@@download/PKBFI5008DXFN.mtx"
}
],
"input_file_set_for": [],
"input_file_sets": [
{
"@id": "/measurement-sets/PKBDS4915KOIO/",
"accession": "PKBDS4915KOIO",
"aliases": [
"klaus-kaestner:HPAP_MeasurementSet_scRNAseq_HPAP-096_no_treatment"
],
"file_set_type": "experimental data"
}
],
"lab": {
"@id": "/labs/klaus-kaestner/",
"title": "Klaus Kaestner, UPenn"
},
"notes": "HPAP",
"release_timestamp": "2025-06-15T04:47:28.639811+00:00",
"samples": [
{
"@id": "/primary-islet/PKBSM2200JUWJ/",
"@type": [
"PrimaryIslet",
"Biosample",
"Sample",
"Item"
],
"accession": "PKBSM2200JUWJ",
"aliases": [
"klaus-kaestner:biosample_HPAP-096"
],
"sample_terms": [
{
"@id": "/sample-terms/UBERON_0000006/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"kyle-gaulton:sample_isletofLangerhans"
],
"status": "released",
"summary": "islet of Langerhans",
"term_name": "islet of Langerhans"
}
],
"status": "released",
"summary": "islet of Langerhans cell, female, Homo sapiens",
"taxa": "Homo sapiens"
}
],
"schema_version": "7",
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitted_files_timestamp": "2025-05-15T23:34:13.745748+00:00",
"submitter_comment": "HPAP-096",
"summary": "intermediate analysis of scRNA-seq data",
"uuid": "a0957a31-733e-4466-9c54-db07893cd159"
}