PKBDS0553EHDS
{
"@context": "/terms/",
"@id": "/analysis-sets/PKBDS0553EHDS/",
"@type": [
"AnalysisSet",
"FileSet",
"Item"
],
"accession": "PKBDS0553EHDS",
"aliases": [
"pankbase-consortium:FunctionalData_AnalysisSet_RRIDSAMN19776444"
],
"assay_titles": [
"an analyte assay that measures the abundance of a hormone"
],
"audit": {
"ERROR": [
{
"category": "unexpected input file set",
"detail": "Analysis set [PKBDS0553EHDS](/analysis-sets/PKBDS0553EHDS/) links to file set(s): [PKBDS5201IBXQ](/measurement-sets/PKBDS5201IBXQ/) in `input_file_sets` that are not represented in the `derived_from` of the file sets of the files in this analysis. The analysis set input files are expected to belong to the input file sets.",
"level": 60,
"level_name": "ERROR",
"name": "audit_input_file_sets_derived_from",
"path": "/analysis-sets/PKBDS0553EHDS/"
}
],
"INTERNAL_ACTION": [
{
"category": "mismatched status",
"detail": "Released tabular file [PKBFI5990MGPK](/tabular-files/PKBFI5990MGPK/) has in progress subobject analysis step version [ce0270c1-3e40-4326-a24e-e142b7caa387](/analysis-step-versions/ce0270c1-3e40-4326-a24e-e142b7caa387/).",
"level": 30,
"level_name": "INTERNAL_ACTION",
"name": "audit_item_status",
"path": "/tabular-files/PKBFI5990MGPK/"
}
],
"WARNING": [
{
"category": "missing tier 1 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 1 field `sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier1_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 2 field `glucose_loweing_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier2_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `diabetes_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `other_therapy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1528QVBI](/human-donors/PKBDO1528QVBI/) is missing tier 3 field `related_donors`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_tier3_fields",
"path": "/human-donors/PKBDO1528QVBI/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM8294NTLC](/primary-islet/PKBSM8294NTLC/) is missing tier 2 field `organ_source`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM8294NTLC/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM8294NTLC](/primary-islet/PKBSM8294NTLC/) is missing tier 2 field `prep_viability`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM8294NTLC/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM8294NTLC](/primary-islet/PKBSM8294NTLC/) is missing tier 2 field `warm_ischaemia_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM8294NTLC/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM8294NTLC](/primary-islet/PKBSM8294NTLC/) is missing tier 2 field `purity`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM8294NTLC/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM8294NTLC](/primary-islet/PKBSM8294NTLC/) is missing tier 2 field `pre_shipment_culture_time`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM8294NTLC/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBSM8294NTLC](/primary-islet/PKBSM8294NTLC/) is missing tier 2 field `islet_function_available`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/primary-islet/PKBSM8294NTLC/"
},
{
"category": "missing derived from",
"detail": "Analysis set [PKBDS0553EHDS](/analysis-sets/PKBDS0553EHDS/) links to file(s) [PKBFI5990MGPK](/tabular-files/PKBFI5990MGPK/) that have no `derived_from`. Files in an analysis set are expected to be derived from other files.",
"level": 40,
"level_name": "WARNING",
"name": "audit_input_file_sets_derived_from",
"path": "/analysis-sets/PKBDS0553EHDS/"
}
]
},
"award": {
"@id": "/awards/UC4DK112217/",
"contact_pi": {
"@id": "/users/e1c8c91f-3952-45a9-9f56-442627f60c13/",
"title": "Klaus Kaestner"
},
"title": "PENN INTEGRATED HUMAN PANCREAS PROCUREMENT AND ANALYSIS PROGRAM"
},
"control_for": [],
"creation_timestamp": "2026-05-21T01:23:55.199201+00:00",
"description": "Analysis of dynamic islet perifusion assay for human donor RRID:SAMN19776444",
"donors": [
{
"@id": "/human-donors/PKBDO1528QVBI/",
"accession": "PKBDO1528QVBI",
"aliases": [
"klaus-kaestner:HPAP-012"
],
"gender": "Female",
"status": "released",
"taxa": "Homo sapiens"
}
],
"file_set_type": "intermediate analysis",
"files": [
{
"@id": "/tabular-files/PKBFI5990MGPK/",
"accession": "PKBFI5990MGPK",
"aliases": [
"pankbase-consortium:FunctionalData_AnalysisSet_RRIDSAMN19776444_hg38_tsv"
],
"content_type": "meta data table",
"creation_timestamp": "2026-05-21T04:29:46.017114+00:00",
"file_format": "tsv",
"href": "/tabular-files/PKBFI5990MGPK/@@download/PKBFI5990MGPK.tsv.gz"
}
],
"input_file_set_for": [],
"input_file_sets": [
{
"@id": "/measurement-sets/PKBDS5201IBXQ/",
"accession": "PKBDS5201IBXQ",
"aliases": [
"pankbase-consortium:FunctionalData_MeasurementSet_RRIDSAMN19776444"
],
"file_set_type": "experimental data"
}
],
"lab": {
"@id": "/labs/klaus-kaestner/"
},
"normalized_glucagon_secretion_units": "pg/100 IEQs/min;%content/min",
"normalized_insulin_secretion_units": "ng/100 IEQs/min;%content/min",
"release_timestamp": "2026-05-21T18:05:13.375372+00:00",
"samples": [
{
"@id": "/primary-islet/PKBSM8294NTLC/",
"@type": [
"PrimaryIslet",
"Biosample",
"Sample",
"Item"
],
"accession": "PKBSM8294NTLC",
"aliases": [
"pankbase-consortium:postShipmentBiosample_RRIDSAMN19776444"
],
"sample_terms": [
{
"@id": "/sample-terms/UBERON_0000006/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"kyle-gaulton:sample_isletofLangerhans"
],
"status": "released",
"summary": "islet of Langerhans",
"term_name": "islet of Langerhans"
}
],
"status": "released",
"summary": "islet of Langerhans cell, Female, Homo sapiens"
}
],
"schema_version": "8",
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitted_files_timestamp": "2026-05-21T04:29:46.017114+00:00",
"submitter_comment": "RRID:SAMN19776444",
"total_glucagon_content": "261507.8 pg",
"total_insulin_content": "1520.3 ng",
"total_islet_cell_volume": 263.73,
"uuid": "460022c6-4b98-4c3c-b6cb-c1498a21d783"
}
Supported by National Institutes of Health (NIH) grants U24 DK138515, U24 DK138512
Supplemental funds from the NIH Office of Data Science Strategies
Supplemental funds from the NIH Office of Data Science Strategies
