{
"@context": "/terms/",
"@id": "/analysis-sets/PKBDS0018GLYX/",
"@type": [
"AnalysisSet",
"FileSet",
"Item"
],
"accession": "PKBDS0018GLYX",
"aliases": [
"klaus-kaestner:pancreaticBetaCell_AnalysisSet_RNAseq_HPAP-097"
],
"assay_titles": [
"RNA-seq"
],
"audit": {
"ERROR": [
{
"category": "unexpected input file set",
"detail": "Analysis set [PKBDS0018GLYX](/analysis-sets/PKBDS0018GLYX/) links to file set(s): [PKBDS4181UXHJ](/measurement-sets/PKBDS4181UXHJ/) in `input_file_sets` that are not represented in the `derived_from` of the file sets of the files in this analysis. The analysis set input files are expected to belong to the input file sets.",
"level": 60,
"level_name": "ERROR",
"name": "audit_input_file_sets_derived_from",
"path": "/analysis-sets/PKBDS0018GLYX/"
},
{
"category": "inconsistent parent sample",
"detail": "Primary cell [PKBSM3404FQQJ](/primary-cells/PKBSM3404FQQJ/) has metadata properties (`islet_function_available`, `rrid`, `islet_histology`, `pancreas_weight`, `sample_terms`, `islet_yield`, `isolation_center`, `lower_bound_age`, `hand_picked`, `cold_ischaemia_time`, `purity`, `age_units`, `islet_morphology`, `upper_bound_age`, `preservation_method`, `prep_viability`, `organ_source`) inconsistent with its associated parent sample [PKBSM6113VWVP](/primary-islet/PKBSM6113VWVP/). Samples that are sorted from or part of a parent sample are expected to share most of the parent's metadata properties.",
"level": 60,
"level_name": "ERROR",
"name": "audit_sample_sorted_from_parent_child_check",
"path": "/primary-cells/PKBSM3404FQQJ/"
}
],
"WARNING": [
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO1701BQMY](/human-donors/PKBDO1701BQMY/) is missing tier 2 field `diabetes_status_hba1c`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/human-donors/PKBDO1701BQMY/"
},
{
"category": "missing tier 2 field",
"detail": "Human donor [PKBDO1701BQMY](/human-donors/PKBDO1701BQMY/) is missing tier 2 field `glucose_loweing_theraphy`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_desired_fields",
"path": "/human-donors/PKBDO1701BQMY/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1701BQMY](/human-donors/PKBDO1701BQMY/) is missing tier 3 field `phenotypic_features`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1701BQMY/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1701BQMY](/human-donors/PKBDO1701BQMY/) is missing tier 3 field `family_history_of_diabetes_relationship`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1701BQMY/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1701BQMY](/human-donors/PKBDO1701BQMY/) is missing tier 3 field `biological_sex`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1701BQMY/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1701BQMY](/human-donors/PKBDO1701BQMY/) is missing tier 3 field `diabetes_duration`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1701BQMY/"
},
{
"category": "missing tier 3 field",
"detail": "Human donor [PKBDO1701BQMY](/human-donors/PKBDO1701BQMY/) is missing tier 3 field `documents`.",
"level": 40,
"level_name": "WARNING",
"name": "audit_optional_fields",
"path": "/human-donors/PKBDO1701BQMY/"
},
{
"category": "missing files",
"detail": "Analysis set [PKBDS0018GLYX](/analysis-sets/PKBDS0018GLYX/) has no `files`. File sets are expected to have files.",
"level": 40,
"level_name": "WARNING",
"name": "audit_no_files",
"path": "/analysis-sets/PKBDS0018GLYX/"
},
{
"category": "missing age",
"detail": "Primary cell [PKBSM3404FQQJ](/primary-cells/PKBSM3404FQQJ/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
"level": 40,
"level_name": "WARNING",
"name": "audit_biosample_age",
"path": "/primary-cells/PKBSM3404FQQJ/"
}
]
},
"award": {
"@id": "/awards/U01DK123594/",
"contact_pi": {
"@id": "/users/e1c8c91f-3952-45a9-9f56-442627f60c13/",
"title": "Klaus Kaestner"
},
"title": "THE HUMAN PANCREAS ANALYSIS PROGRAM FOR TYPE 2 DIABETES"
},
"collections": [
"HPAP"
],
"control_for": [],
"creation_timestamp": "2024-12-05T18:11:09.376022+00:00",
"description": "Analysis set of RNA-seq for pancreatic beta cell of islet biosample from human donor SAMN22562808 in the HPAP database HPAP-097",
"donors": [
{
"@id": "/human-donors/PKBDO1701BQMY/",
"accession": "PKBDO1701BQMY",
"aliases": [
"klaus-kaestner:HPAP-097"
],
"sex": "female",
"status": "released",
"taxa": "Homo sapiens"
}
],
"file_set_type": "intermediate analysis",
"files": [],
"input_file_set_for": [],
"input_file_sets": [
{
"@id": "/measurement-sets/PKBDS4181UXHJ/",
"accession": "PKBDS4181UXHJ",
"aliases": [
"klaus-kaestner:pancreaticBetaCell_MeasurementSet_RNAseq_HPAP-097"
],
"file_set_type": "experimental data"
}
],
"lab": {
"@id": "/labs/klaus-kaestner/",
"title": "Klaus Kaestner, UPenn"
},
"publication_identifiers": [
"PMID:31127054",
"PMCID:PMC6609987",
"doi:10.2337/db19-0058",
"PMID:36206763",
"PMCID:PMC9742126",
"doi:10.1016/j.cmet.2022.09.013"
],
"release_timestamp": "2025-01-10T10:14:06.169433+00:00",
"samples": [
{
"@id": "/primary-cells/PKBSM3404FQQJ/",
"@type": [
"PrimaryCell",
"Biosample",
"Sample",
"Item"
],
"accession": "PKBSM3404FQQJ",
"aliases": [
"klaus-kaestner:pancreaticBetaCell_HPAP-097"
],
"sample_terms": [
{
"@id": "/sample-terms/CL_0000169/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"kyle-gaulton:sample_typeBpancreaticCell"
],
"status": "released",
"summary": "type B pancreatic cell",
"term_name": "type B pancreatic cell"
}
],
"status": "released",
"summary": "type B pancreatic cell, female, Homo sapiens",
"taxa": "Homo sapiens"
}
],
"schema_version": "7",
"status": "released",
"submitted_by": {
"@id": "/users/5e3038c4-baa5-4589-b3d8-ad2fe634e826/",
"title": "Ying Sun"
},
"submitter_comment": "HPAP-097",
"summary": "intermediate analysis of RNA-seq data",
"uuid": "6bed57b8-9da8-4bf4-b38c-0febaf2d7bd8"
}